C4582

β-Carotene

synthetic, ≥95% (HPLC), crystalline

• Synonyme(s) : β,β-Carotene, Provitamin A
• Formule empirique (notation de Hill): C₄₀H₅₆
• Numéro CAS: 7235-40-7
• Poids moléculaire : 536.87
• Beilstein: 1917416
• Numéro CE : 230-636-6
• Numéro MDL: MFCD00001556
• Code UNSPSC : 12352212
• ID de substance PubChem : 24892702
• Nomenclature NACRES : NA.77

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 200
• Essai: ≥95% (HPLC)
• Forme: crystalline
• Impuretés: α-carotene, essentially free
• Couleur: dark red-purple to red-brown
• Pf: 178-179 °C
• Solubilité: hexane: soluble 100 μg/mL; DMSO: 30 μg/mL; H₂O: insoluble
• ε (coefficient d'extinction): 2160-2280 at 478-479 nm in hexane at 1% (vs. 2280, lit.); 2450-2590 at 450-452 nm in hexane at 1% (vs. 2590, lit.)
• Température de stockage: −20°C
• Chaîne SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1
• InChI: 1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
• Clé InChI: OENHQHLEOONYIE-JLTXGRSLSA-N

Description

Application

β-Carotene has been used:

• as standard for quantification of b-carotene using HPLC analysis[1]
• as a standard for the identification and quantification of authentic standards for carotenoid groups[2]
• for standard curve preparation in the measurement of β-carotene production[3]
• for standard curve preparation in nutritive assays[4]

Actions biochimiques/physiologiques

β-Carotene (pro-vitamin A) is a member of carotenoids. This antioxidant plays a vital role in human physiology.[5] β-Carotene is an abundant carotenoid. It is considered as a precursor of vitamin A, which is a lipid soluble antioxidant with vitamin E properties.[5][6]

The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.

The most important of the provitamins A.

Attention

Purchase minimum quantity required. Discard one month after opening.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 217.9 °F - closed cup
• Point d'éclair (°C): 103.3 °C - closed cup
• Équipement de protection individuelle: Eyeshields, Gloves