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Key Documents

C9750

Sigma-Aldrich

β-Carotene

synthetic, ≥93% (UV), powder

Synonyme(s) :

β,β-Carotene, Provitamin A

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About This Item

Formule empirique (notation de Hill):
C40H56
Numéro CAS:
Poids moléculaire :
536.87
Numéro Beilstein :
1917416
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352205
ID de substance PubChem :
Nomenclature NACRES :
NA.79

Source biologique

synthetic

Pureté

≥93% (UV)

Forme

powder

Puissance

~1,600,000 units vitamin A per g

Couleur

dark red to brown

Pf

178-179 °C

Solubilité

hexane: 1.1 mg/mL
DMSO: 30 μg/mL

Température de stockage

−20°C

Chaîne SMILES 

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+

Clé InChI

OENHQHLEOONYIE-JLTXGRSLSA-N

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Description générale

Carotenoids are an important class of naturally occurring pigments found in fruits and vegetables. Among the carotenoids, β-carotene has the greatest provitamin A potential and functions to reduce the risk of cancer, cardiovascular diseases and macular degeneration. Low water solubility and poor chemical stability attributes to low absorption of β-carotene from food. β-carotene along with digestible lipids enriches its bio accessibility. Emulsions or nano emulsions encapsulates effectively delivers lipophilic β-carotene and increases its bioavailability. β-carotene has anti-oxidant potential and reduces noise induced hearing loss and progression of macular degeneration.

Application

β-carotene has been used:
  • to generate nano emulsions to evaluate their bioavailability potential
  • as a standard, for β-carotene evaluation in blood and skin samples using high performance liquid chromatography (HPLC),
  • as a dietary supplement of vitamin-A in young rats by HPLC
  • as a dietary supplement in mice to reduce hearing loss and hair cell damage

Actions biochimiques/physiologiques

The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.

Conditionnement

Packaged in serum vials.

Attention

Purchase minimum quantity required. Discard one month after opening.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

217.9 °F - closed cup

Point d'éclair (°C)

103.3 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves


Certificats d'analyse (COA)

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