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Key Documents

04231

Sigma-Aldrich

Calcium phosphate dibasic dihydrate

puriss., meets analytical specification of Ph. Eur., BP, USP, 98-102.5%

Synonyme(s) :

Calcium hydrogen phosphate dihydrate

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About This Item

Formule linéaire :
CaHPO4 · 2H2O
Numéro CAS:
Poids moléculaire :
172.09
Numéro CE :
Numéro MDL:
Code UNSPSC :
51101500
ID de substance PubChem :
Nomenclature NACRES :
NA.21

Qualité

puriss.
meets analytical specification of Ph. Eur., BP, USP

Pureté

98-102.5%

Forme

powder

Impuretés

organic volatile impurities, complies
residual solvents, complies
≤0.003% heavy metals (as Pb)
≤0.1% insoluble in HCl

Perte

24.5-26.5% loss on ignition, 800 °C

Traces d'anions

carbonate (CO32-): in accordance
chloride (Cl-): ≤200 mg/kg
fluoride (F-): ≤50 mg/kg
sulfate (SO42-): ≤3000 mg/kg

Traces de cations

As: ≤1 mg/kg
Ba:, in accordance (Ph Eur)
Ba:, in accordance (USP)
Fe: ≤300 mg/kg

Chaîne SMILES 

O.O.[Ca++].OP([O-])([O-])=O

InChI

1S/Ca.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+2;;;/p-2

Clé InChI

XAAHAAMILDNBPS-UHFFFAOYSA-L

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Application


  • Simultaneous Regulation of the Mechanical/Osteogenic Capacity of Brushite Calcium Phosphate Cement by Incorporating with Poly(ethylene glycol) Dicarboxylic Acid: This research investigates enhancing brushite calcium phosphate cements by adding poly(ethylene glycol) dicarboxylic acid to improve mechanical properties and osteogenic capabilities, applicable in bone regeneration and implant materials. (Gao et al., 2024).

  • Biosurfactant-Assisted Cu Doping of Brushite Coatings: Explores the structural and biofunctional enhancements of brushite coatings through copper doping facilitated by biosurfactants, which could revolutionize surface treatments for biocompatible implants and devices. (Siva Prasad et al., 2024).

  • Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair: This study highlights the application of calcium phosphate dibasic dihydrate in developing protective coatings on magnesium-based implants, significantly advancing orthopedic and dental implant technologies. (Wu et al., 2024).

  • Physiologically Engineered Porous Titanium/Brushite Scaffolds for Critical-Size Bone Defects: Details the design and fabrication of novel scaffolds for treating large bone defects, utilizing a combination of titanium and brushite, highlighting its potential in reconstructive surgery and regenerative medicine. (Abdulaziz et al., 2023).

  • Mechanochemical Synthesis of Cerium Chlorapatite from a Mixture of Cerium Chloride Heptahydrate, Dicalcium Phosphate Dihydrate, and Calcium Hydroxide for Biomedical Application: Focuses on the innovative production of cerium chlorapatite using dicalcium phosphate dihydrate, showcasing its potential in biomedical engineering, especially in drug delivery and tissue engineering. (Otsuka et al., 2024).

Pictogrammes

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Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Moreton, R. C.
Chemical & Pharmaceutical Bulletin, 868-870 (1996)
J M Lausier et al.
Journal of pharmaceutical sciences, 66(11), 1636-1637 (1977-11-01)
The aging of direct compression tablets made using dibasic calcium phosphate dihydrate as the tablet matrix was investigated over 16 weeks. The formula included 6% amaranth as a dye tracer. Two sets of stress storage conditions were used: 25 degrees
F Michaut et al.
Journal of pharmaceutical sciences, 99(6), 2874-2885 (2009-12-30)
The Stylcam 100R, a rotary press simulator, was designed to simulate speed profiles of rotary tablet presses. Such a simulator was qualified by numerous laboratories and, actually, its ability to be used for studying the behaviour of powders under pressure
Silvia Panzavolta et al.
Journal of inorganic biochemistry, 105(8), 1060-1065 (2011-07-06)
We previously proposed a biomimetic α-tricalcium phosphate (α-TCP) bone cement where gelatin controls the transformation of α-TCP into calcium deficient hydroxyapatite (CDHA), leading to improved mechanical properties. In this study we investigated the setting and hardening processes of biomimetic cements
Sarsvatkumar Patel et al.
International journal of pharmaceutics, 389(1-2), 66-73 (2010-01-20)
This work proposed to study the influence of varying compaction pressure on the plastic energy, elasticity (Young's modulus), particle yield strength, strain hardening, and applied pressures on derived Heckel parameter using material with different densification and deformation mechanisms: ibuprofen (IBN)

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