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Key Documents

COO/COA

Y0001416

Betamethasone dipropionate for peak identification

Name: Betamethasone dipropionate for peak identification
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

Betamethasone 17,21-dipropionate, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate

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About This Item

Formule empirique (notation de Hill):

C₂₈H₃₇FO₇

Numéro CAS:

5593-20-4

Poids moléculaire :

504.59

Numéro MDL:

MFCD00133140

Code UNSPSC :

41116107

ID de substance PubChem :

329831413

Nomenclature NACRES :

NA.24

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Betamethasone dipropionate

USP

1067704

Betamethasone dipropionate

B0305000

Beclomethasone dipropionate

Y0000637

Azithromycin for peak identification

Y0000473

Calcipotriol monohydrate

Y0000307

Azithromycin impurity A

Y0001925

Betamethasone dipropionate for system suitability A

M2900000

Mometasone furoate

Supelco

PHR1619

Beclomethasone Dipropionate

Qualité

pharmaceutical primary standard

Famille d'API

betamethasone

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES

[H][C@@]12C[C@H](C)[C@](OC(=O)CCl)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)C3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

1S/C27H34ClFO7/c1-5-22(33)35-14-21(32)27(36-23(34)13-28)15(2)10-19-18-7-6-16-11-17(30)8-9-24(16,3)26(18,29)20(31)12-25(19,27)4/h8-9,11,15,18-20,31H,5-7,10,12-14H2,1-4H3/t15-,18-,19-,20-,24-,25-,26?,27-/m0/s1

Clé InChI

UOCNBCVPZWLUKX-HOBFILNXSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betamethasone dipropionate for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

Betamethasone 17,21-dipropionate is a glucocorticoid with anti-inflammatory and immunosuppressive activity.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit

Description

Tarif

Mention d'avertissement

Danger

Mentions de danger

H360FD,H373

Conseils de prudence

P202 - P260 - P280 - P308 + P313 - P405 - P501

Classification des risques

Repr. 1B - STOT RE 2

Organes cibles

Liver,Kidney,Endocrine system

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

Désolés, nous n'avons pas de COA pour ce produit disponible en ligne pour le moment.

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Cost effectiveness of the two-compound formulation calcipotriol and betamethasone dipropionate gel in the treatment of scalp psoriasis in Scotland.

Andrew G Affleck et al.

Current medical research and opinion, 27(1), 269-284 (2010-12-15)

To compare the cost effectiveness of the two-compound formulation (TCF) calcipotriol plus betamethasone dipropionate gel used first-, second- or third-line to standard topical treatments for moderately severe scalp psoriasis from a Scottish NHS perspective. Treatment pathways for scalp psoriasis patients

Mixed treatment comparison of a two-compound formulation (TCF) product containing calcipotriol and betamethasone dipropionate with other topical treatments in psoriasis vulgaris.

Peter van de Kerkhof et al.

Current medical research and opinion, 27(1), 225-238 (2010-12-15)

The efficacy of the two-compound formulation (TCF) product containing calcipotriol and betamethasone dipropionate applied once daily in psoriasis has been demonstrated in phase III trials but no randomised clinical trial comparing all commonly used topical treatments exists. The aim of

The effectiveness of two-compound formulation calcipotriol and betamethasone dipropionate gel in the treatment of moderately severe scalp psoriasis: a systematic review of direct and indirect evidence.

Julia M Bottomley et al.

Current medical research and opinion, 27(1), 251-268 (2010-12-15)

To evaluate the two-compound formulation (TCF) calcipotriol and betamethasone dipropionate (BDP) gel versus other topical therapies for scalp psoriasis in adults using direct and indirect comparisons. A systematic review identified 10 randomised controlled trials (RCTs) of topical treatments used in

[The calcipotriol-betamethasone dipropionate association].

F Henry et al.

Revue medicale de Liege, 60(11), 893-895 (2006-01-13)

The topical treatment of psoriasis benefits from the alternate use of dermocorticosteroids and vitamin D3 analogues. A new galenic formulation allows to combine them in a single application. Dovobet (LEO Pharma) ointment is the association of calcipotriol 50 microg/g with

Calcipotriol/betamethasone dipropionate: a review of its use in the treatment of psoriasis vulgaris of the trunk, limbs and scalp.

Paul L McCormack

Drugs, 71(6), 709-730 (2011-04-21)

Calcipotriol/betamethasone dipropionate (calcipotriol 50 μg/g and betamethasone 0.5 mg/g) is a fixed-dose combination of a vitamin D(3) analogue and a corticosteroid indicated for the once-daily, topical treatment of psoriasis vulgaris of the trunk, limbs and scalp in adults. Both the ointment (Daivobet®;

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