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Principaux documents

COO/COA

T1410900

Tiaprofenic acid

Name: Tiaprofenic acid
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

(±)-Tiaprofenic acid

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About This Item

Formule empirique (notation de Hill):

C₁₄H₁₂O₃S

Numéro CAS:

33005-95-7

Poids moléculaire :

260.31

Code UNSPSC :

41116107

Nomenclature NACRES :

NA.24

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USP

1642507

Suprofen

Sigma-Aldrich

N5285

Neomycin trisulfate salt hydrate

T1410910

Tiaprofenic acid impurity C

USP

1006801

Acétone

USP

1442009

Metronidazole

Roche

11284932001

DNase I

Sigma-Aldrich

G1914

Gentamicine sulfate

USP

1381709

(−)-Menthol

Supelco

1.00573

Acide orthophosphorique (85 %)

Roche

10104159001

DNase I

Qualité

pharmaceutical primary standard

Famille d'API

tiaprofenic acid

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

InChI

1S/C14H12O3S/c1-9(14(16)17)11-7-8-12(18-11)13(15)10-5-3-2-4-6-10/h2-9H,1H3,(H,16,17)

Clé InChI

GUHPRPJDBZHYCJ-UHFFFAOYSA-N

Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Tiaprofenic acid EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

GHS06,GHS08

Mention d'avertissement

Danger

Mentions de danger

H301,H361

Conseils de prudence

P201 - P301 + P310 + P330

Classification des risques

Acute Tox. 3 Oral - Repr. 2

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

The long-term effects of non-steroidal anti-inflammatory drugs in osteoarthritis of the knee: a randomized placebo-controlled trial.

D L Scott et al.

Rheumatology (Oxford, England), 39(10), 1095-1101 (2000-10-18)

Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used to treat osteoarthritis (OA), though their long-term efficacy is uncertain. We report a comparison of the symptomatic responses to therapy with tiaprofenic acid, indomethacin and placebo over 5 yr. A parallel-group, randomized, single-blind

Differential effects of nonsteroidal antiinflammatory drugs on the IL-1 altered expression of plasminogen activators and plasminogen activator inhibitor-1 by articular chondrocytes.

T Sadowski et al.

Inflammation research : official journal of the European Histamine Research Society ... [et al.], 51(8), 427-433 (2002-09-18)

To determine the in vitro effects of several nonsteroidal antiinflammatory drugs on the IL-1 altered expression and activity of tPA, uPA and PAI-1 by articular chondrocytes. Bovine chondrocytes were cultured in alginate gel beads. Cells were treated with IL-1alpha in

Antibodies directed to drug epitopes to investigate the structure of drug-protein photoadducts. Recognition of a common photobound substructure in tiaprofenic acid/ketoprofen cross-photoreactivity.

A Lahoz et al.

Chemical research in toxicology, 14(11), 1486-1491 (2001-11-20)

Drug-induced photoallergy is an immune adverse reaction to the combined effect of drugs and light. From the mechanistic point of view, it first involves covalent binding of drug to protein resulting in the formation of a photoantigen. Hence, determination of

Clinical features of tiaprofenic acid (surgam) associated cystitis and a study of risk factors for its development.

R Buchbinder et al.

Journal of clinical epidemiology, 53(10), 1013-1019 (2000-10-12)

A case-control study was performed to describe the clinical course and identify risk factors predisposing to the development of tiaprofenic acid associated cystitis. Cases were identified from reports to the Australian Adverse Drug Reactions Advisory Committee and a two-year (1995-1996)

Jana G Hashash et al.

Clinical therapeutics, 29(11), 2448-2452 (2007-12-26)

A 40-year-old previously healthy white man presented to the emergency department at American University of Beirut Medical Center, Beirut, Lebanon, with severe upper abdominal pain of 36-hour duration. The pain started a few hours after the intake of a single

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