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AOZ

VETRANAL®, analytical standard

Synonyme(s) :

3-Amino-2-oxazolidinone, NSC 111187, NSC 196570, NSC 38250

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About This Item

Formule empirique (notation de Hill):
C3H6N2O2
Numéro CAS:
Poids moléculaire :
102.09
Numéro Beilstein :
109430
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

Gamme de produits

VETRANAL®

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Pf

63-69 °C

Adéquation

passes test for identity

Application(s)

clinical testing

Format

neat

Chaîne SMILES 

NN1CCOC1=O

InChI

1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2

Clé InChI

KYCJNIUHWNJNCT-UHFFFAOYSA-N

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Description générale

AOZ, also known as 3-amino-2-oxazolidinone, is a metabolite of the synthetic nitrofuran veterinary antibiotic ― furazolidone.

Application

The analytical standard can be used as follows:
  • Development of an electrochemical impedimetric immunosensor based on immobilization of a monoclonal antibody on a gold electrode, to determine AOZ in six food samples
  • Multi-residue analysis of four nitrofuran metabolites residues in 120 fish samples by ultra high-performance liquid chromatography (UHPLC) combined with tandem mass spectrometry
  • Detection and measurement of AOZ in tissue samples obtained from four animals by immunochromatography test stripes based on colloidal gold-monoclonal antibody
  • LC-MS/MS analysis of nitrofuran and nitroimidazole metabolite residues in honey samples after their extraction by a modified QuEChERS-based method
  • Screening of nitrofuran metabolite residues from shrimp muscle samples by an HPLC method combined with diode array detection

Autres remarques

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Monoclonal antibody-based ELISA for the quantification of nitrofuran metabolite 3-amino-2-oxazolidinone in tissues using a simplified sample preparation
Diblikova I, et al.
Analytica Chimica Acta, 540, 285-292 (2005)
Quan Wang et al.
Analytical and bioanalytical chemistry, 410(1), 223-233 (2017-11-01)
There is an urgent need for the rapid and simultaneous detection of multiple analytes present in a sample matrix. Here, a multiplex immunochromatographic test (multi-ICT) was developed that successfully allowed for the rapid and simultaneous detection of four major nitrofuran
Kangkang Wang et al.
ACS omega, 5(30), 18887-18893 (2020-08-11)
Nitrofuran (NF) is a class of broad-spectrum antibiotics that are used illegally in animal feeding. NF and its metabolites have proven to pose potential risk to human health. To address the current analytical needs to quantify low levels of NF
EunChae Ryu et al.
Environmental science and pollution research international, 28(6), 7551-7563 (2020-10-11)
A simplified method is described for reducing the analysis time of nitrofurans (NFs) and nitrofuran metabolites (NFMs) in the aquatic animals. Most existing HPLC-MS/MS methods are intended only for NFMs and are based on their fast metabolic transformations. We optimized
Pierre Guichard et al.
Food chemistry, 342, 128389-128389 (2020-12-04)
LC-MS/MS method for confirmation of nitrofuran metabolites in meat and aquaculture products, including the nifursol metabolite (DNSH), was developed. The nitrofuran metabolites investigated were as follows: 3-amino-2-oxazolidinone (AOZ), 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), 1-aminohydantoine (AHD), semicarbazide (SEM) and 3,5-dinitrosalicylic acid hydrazide (DNSH). The

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