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850524P

Avanti

CHEMS

Avanti Research™ - A Croda Brand

Synonyme(s) :

3β-Hydroxy-5-cholestene 3-hemisuccinate; 5-Cholesten-3β-ol 3-hemisuccinate; CHS

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About This Item

Formule empirique (notation de Hill) :
C31H50O4
Numéro CAS:
1510-21-0
Poids moléculaire :
486.73
Numéro MDL:
MFCD00037705
Code UNSPSC :
12161902
Nomenclature NACRES :
NA.25

Description

cholesteryl hemisuccinate

Essai

>99% (TLC)

Forme

powder

Poids mol.

486.73 g/mol

Conditionnement

pkg of 1 × 1 g (850524P-1g)
pkg of 1 × 5 g (850524P-5g)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand

Technique(s)

protein quantification: suitable

Application(s)

cell analysis

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

O([C@H]1CC[C@@]2([C@@H]3[C@H]([C@H]4[C@@]([C@H](CC4)[C@@H](CCCC(C)C)C)(CC3)C)CC=C2C1)C)C(=O)CCC(=O)O

InChI

1S/C31H50O4/c1-20(2)7-6-8-21(3)25-11-12-26-24-10-9-22-19-23(35-29(34)14-13-28(32)33)15-17-30(22,4)27(24)16-18-31(25,26)5/h9,20-21,23-27H,6-8,10-19H2,1-5H3,(H,32,33)/t21-,23+,24+,25-,26+,27+,30+,31-/m1/s1

Clé InChI

WLNARFZDISHUGS-MIXBDBMTSA-N

Catégories apparentées

Description générale

Cholesteryl hemisuccinate (CHEMS) is an acidic cholesterol ester.

Application

CHEMS is suitable:
  • to prepare multifunctional envelope-type nano device (MEND) by a lipid film hydration method based on electrostatic interactions
  • to as a component in bolavesicle
  • to prepare liposome (LS)
  • for the preparation of anionic liposomes by the lipid thin film hydration and freeze/thaw technique and to encapsulate ovalbumin (OVA) and listeriolysin O (LLO)
  • to prepare liposomal membranes to study its effect on the physical–chemical properties of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) liposomes

Actions biochimiques/physiologiques

CHEMS can help to maintain the stability of dioleoylphosphatidylethanolamine (DOPE). This amphipathic lipid is used in mixtures with dioleoylphosphatidylethanolamine (DOPE) to form ′pH sensitive′ fusogenic vesicles. It can control cell growth.

Conditionnement

20 mL Clear Glass Screw Cap Vial (850524P-1g)
30 mL Amber Wide Mouth Glass Bottle with Screw Cap (850524P-5g)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Lipogels for Encapsulation of Hydrophilic Proteins and Hydrophobic Small Molecules
Homyak CC, et al.
Biomacromolecules, 19(1), 132-140 (2017)
Yongrong Yao et al.
Biomaterials science, 8(1), 256-265 (2019-11-07)
Chemotherapy is a dominant treatment modality for different types and stages of cancer. However, hypoxia is one of the undesirable limitations of chemotherapy, which reduces the therapeutic efficiency in cancer treatment, ultimately leading to failure of the treatment. Herein, an
Bolaamphiphilic vesicles encapsulating iron oxide nanoparticles: New vehicles for magnetically targeted drug delivery
Philosof-Mazor L, et al.
International Journal of Pharmaceutics, 450(1-2), 241-249 (2013)
Preparation and evaluation of multifunctional envelope-type nano device loading siRNA
Yin H, et al.
Artificial Cells, Nanomedicine, and Biotechnology (Print), 44(1), 20-26 (2016)
Enhanced in vivo gene expression mediated by listeriolysin O incorporated anionic LPDII: Its utility in cytotoxic T lymphocyte-inducing DNA vaccine
Sun X, et al.
J. Controlled Release, 148(2), 219-225 (2010)
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