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C91492

Sigma-Aldrich

Bromure de cyanogène

reagent grade, 97%

Synonyme(s) :

Bromine cyanide

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About This Item

Formule linéaire :
BrCN
Numéro CAS:
Poids moléculaire :
105.92
Beilstein:
1697296
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352100
ID de substance PubChem :
Nomenclature NACRES :
NA.22
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Qualité

reagent grade

Niveau de qualité

Densité de vapeur

3.65 (vs air)

Pression de vapeur

100 mmHg ( 22.6 °C)

Essai

97%

Forme

crystals

pb

61-62 °C (lit.)

Pf

50-53 °C (lit.)

Température de stockage

2-8°C

Chaîne SMILES 

BrC#N

InChI

1S/CBrN/c2-1-3

Clé InChI

ATDGTVJJHBUTRL-UHFFFAOYSA-N

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Description générale

Cyanogen bromide (CNBr) is a halogen halide. Its utility as a condensing agent during chemical ligation of oligodeoxyribonucleotides has been reported.[1] Its threshold photoelectron (TPE) spectrum has been recorded under high resolution.[2] The cryopolymerization of CNBr on irradiation has been investigated.[3]

Application

Cyanogen bromide may be used:
  • To activate polysaccharides for coupling with erythrocytes.[4]
  • As an oxidizing agent in urine thaimine assay.[5]
  • In the preparation of 2-amino-5-(2′-thienyl)-1,3,4-oxadiazole.[6]
For peptide cleavage[7] and use in protein immobilization procedures.[8] Reaction with C60Ph5Cl produces a novel phenylated isoquinolino[3′,4′:1,2][60]fullerene.[9]

Pictogrammes

Skull and crossbonesCorrosionEnvironment

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1B

Risques supp

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

>149.0 °F - closed cup

Point d'éclair (°C)

> 65 °C - closed cup

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges, type P3 (EN 143) respirator cartridges


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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Org. Mass Spectrom., 28, 1395-1395 (1993)
Applied Biochemistry and Biotechnology, 44, 135-135 (1994)
N I Sokolova et al.
FEBS letters, 232(1), 153-155 (1988-05-09)
Cyanogen bromide was found to condense oligodeoxyribonucleotides on a complementary template in aqueous solution. Optimum conditions for this vigorous and effective reaction were developed. CNBr proved to be useful for incorporation of phosphoramidate or pyrophosphate internucleotide bonds in DNA duplexes.
Threshold photoelectron spectroscopy of cyanogen bromide.
Yencha AJ, et al.
Chemical Physics Letters, 392(1), 202-208 (2004)
Abdul-Sada, A.K. et al.
Chemical Communications (Cambridge, England), 307-307 (1998)

Questions

1–3 of 3 Questions  
  1. Hi, is this sterile and suitable for cell culture? Thank you.

    1 answer
    1. This product is not sterile and has not been tested for cell culture applications. Therefore, it may not be suitable for use in cell culture without proper sterilization procedures.

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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