907383

Fmoc-L-Photo-Lysine

≥95%

• Synonyme(s) : N²-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N⁶-[[2-(3-methyl-3H-diazirin-3-yl)ethoxy]carbonyl]-L-lysine
• Formule empirique (notation de Hill): C₂₆H₃₀N₄O₆
• Numéro CAS: 2250437-42-2
• Poids moléculaire : 494.54
• Code UNSPSC : 12352209

Propriétés

• Pureté: ≥95%
• Forme: solid
• Capacité de réaction: reaction type: Fmoc solid-phase peptide synthesis
• Application(s): peptide synthesis
• Groupe fonctionnel: Fmoc
• Température de stockage: 2-8°C

Description

Application

Fmoc-L-Photo-Lysine is a diazirine-containing, Fmoc-protected lysine amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An unprotected version is also available as 907251.

Autres remarques

Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis

Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs)

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable