PHL82481

Aurapten

phyproof^® Reference Substance

• Synonyme(s) : Auraptene, 7-Geranyloxycoumarin, 7-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-2H-1-benzopyran-2-one, Aurapten
• Formule empirique (notation de Hill) : C₁₉H₂₂O₃
• Numéro CAS: 495-02-3
• Poids moléculaire : 298.38
• Numéro MDL: MFCD00075948
• Code UNSPSC : 41116107
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: primary reference standard
• Gamme de produits: phyproof^® Reference Substance
• Essai: ≥90.0% (HPLC)
• Forme: solid
• Fabricant/nom de marque: PhytoLab
• Température de stockage: 2-8°C
• Chaîne SMILES: C\C(C)=C\CC\C(C)=C\COc1ccc2C=CC(=O)Oc2c1
• InChI: 1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+
• Clé InChI: RSDDHGSKLOSQFK-RVDMUPIBSA-N

Description

Description générale

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Actions biochimiques/physiologiques

Auraptene is an ACAT inhibitor and estrogen receptor modulator.

Auraptene is an estrogen receptor modulator that also acts as an ACAT inhibitor. It displays anti-tumor effects in several xenograft and chemically-induced murine tumor models. Auraptene induces apoptosis and is anti-proliferative in cancer cell lines. It has agonistic properties against PPARs, and interferes with lipid and cholesterol production by inhibiting ACAT (IC50 = 4 uM).

Informations légales

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Informations sur la sécurité

• Code de la classe de stockage: 13 - Non Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable