SAB4500367
Anti-Collagen III antibody produced in rabbit
affinity isolated antibody
Synonyme(s) :
COL3A1, Collagen α-1(III) chain
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About This Item
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41
Produits recommandés
Source biologique
rabbit
Conjugué
unconjugated
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Forme
buffered aqueous solution
Poids mol.
antigen 138 kDa
Espèces réactives
mouse, human, rat
Concentration
~1 mg/mL
Technique(s)
ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... COL3A1(1281)
Catégories apparentées
Description générale
Anti-Collagen III Antibody detects endogenous levels of total Collagen III protein.
Collagen III is also termed as collagen type III α1 (COL3A1). It is a fibrillar collagen present in extensible connective tissues. COL3A1 spans around 44 kb in length and has 52 exons. It is expressed in blood vessels and hollow organs. Collagen III gene is located on human chromosome 2q32.2.
Collagen III is also termed as collagen type III α1 (COL3A1). It is a fibrillar collagen present in extensible connective tissues. COL3A1 spans around 44 kb in length and has 52 exons. It is expressed in blood vessels and hollow organs. Collagen III gene is located on human chromosome 2q32.2.
Immunogène
The antiserum was produced against synthesized peptide derived from human Collagen III.
Immunogen Range: 81-130
Immunogen Range: 81-130
Application
Anti-Collagen III antibody has been used in immunohistochemistry.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry (1 paper)
Actions biochimiques/physiologiques
Collagens usually help in the development of fibrillar and microfibrillar networks of the extracellular matrix, basement membranes and structures of the extracellular matrix. Mutations in the COL3A1 gene results in vascular ehlers-danlos syndrome (vEDS). COL3A1 controls the expression and modulation of collagen.
Caractéristiques et avantages
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Forme physique
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Réf. du produit
Description
Tarif
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
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Les clients ont également consulté
Amrendra Mishra et al.
Nature metabolism, 3(10), 1342-1356 (2021-10-16)
Diet-induced obesity is a major risk factor for metabolic syndrome, diabetes and cardiovascular disease. Here, we show that a 5-d fasting-mimicking diet (FMD), administered every 4 weeks for a period of 2 years, ameliorates the detrimental changes caused by consumption
A new candidate substrate for cell-matrix adhesion study: the acellular human amniotic matrix.
Guo Q, et al.
BioMed Research International, 2012 (2012)
Eri Ohto-Fujita et al.
Cell and tissue research, 376(1), 123-135 (2018-11-19)
Signs of aging in facial skin correlate with lifespan and chronic disease; however, the health of aging skin has not been extensively studied. In healthy young skin, the dermis forms a type III collagen-rich dermal papilla, where capillary vessels supply
Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7.
Su B, et al.
Molecular Cancer, 13(1), 206-206 (2014)
Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease.
Muckian C, et al.
Blood, 100(4), 1220-1223 (2002)
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