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RAB0747

Sigma-Aldrich

Human TF / Serotransferrin ELISA Kit

Synonyme(s) :

Serotransferrin, TF, Transferrin

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About This Item

Code UNSPSC :
41116158
Nomenclature NACRES :
NA.32
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Espèces réactives

human

Conditionnement

kit of 96 wells (12 strips x 8 wells)

Technique(s)

ELISA: suitable

Entrée

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 ng/mL
standard curve range: 1.029-750 ng/mL

Méthode de détection

colorimetric

Conditions d'expédition

wet ice

Température de stockage

−20°C

Informations sur le gène

human ... TF(7018)

Description générale

Transferrin (TF) is an iron (Fe) transport protein and found in blood plasma and brain extracellular fluids. It belongs to the family of Fe-binding glycoproteins. TF is made of a single polypeptide chain with two domains and each domain consists of a Fe-binding site. It helps in the transport of Fe(III) between the cells in soluble and non-toxic forms. TF also acts as a bacteriostatic agent as well as a growth factor. It binds to the transferrin receptor to mediate the cellular uptake of bound Fe.[1] The TF gene is mapped on the human chromosome at 3q22.1.[2] The antibody pair provided in this kit recognizes human serotransferrin.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Autres remarques

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Description
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Pictogrammes

Corrosion

Mention d'avertissement

Warning

Mentions de danger

Conseils de prudence

Classification des risques

Met. Corr. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Rosario Toro-Campos et al.
BMC pediatrics, 20(1), 225-225 (2020-05-20)
A central aim for pediatric nutrition is to develop infant formula compositionally closer to human milk. Milk fat globule membranes (MFGM) have shown to have functional components that are found in human milk, suggesting that addition of bovine sources of
Dahai Jiang et al.
Scientific reports, 10(1), 13334-13334 (2020-08-10)
Niemann-Pick C1 (NPC1) is a lysosomal cholesterol storage disorder, that severely affects the brain, and is caused by mutations in the NPC1 gene, which encodes an intracellular membrane transporter of non-esterified cholesterol. Therapeutic options for NPC1 are few, and classical
Maria Schwarz et al.
Nutrients, 11(9) (2019-09-08)
Trace elements, like Cu, Zn, Fe, or Se, are important for the proper functioning of antioxidant enzymes. However, in excessive amounts, they can also act as pro-oxidants. Accordingly, trace elements influence redox-modulated signaling pathways, such as the Nrf2 pathway. Vice
Sanjay R Mehta et al.
Journal of neuroinflammation, 14(1), 72-72 (2017-04-01)
Mitochondria are abundant organelles critical for energy metabolism and brain function. Mitochondrial DNA (mtDNA), released during cellular injury and as part of the innate immune response to viral pathogens, contains CpG motifs that act as TLR-9 ligands. We investigated relationships
Torsten Arndt et al.
Clinica chimica acta; international journal of clinical chemistry, 394(1-2), 42-46 (2008-04-30)
An incomplete separation of disialotransferrin (CDT) and trisialotransferrin (a non-CDT isoform) may cause false-positive CDT results in alcohol abuse testing. We describe a currently unknown disialotransferrin-trisialotransferrin-bridging phenomenon (di-tri-bridge) appearing with high prevalence in serum from liver cirrhosis patients. Twenty one

Questions

  1. いつもお世話になっております。 RAB0747のhuman Tf ELISA kitですが、マウスTfに対するcross-reactivityがあるのかないのか教えてください。

    1 answer
    1. This product has only been qualified for the detection of the human Tf / Serotransferrin protein. It has not be validated for the mouse Tf / Serotransferrin protein.

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