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P6902

Sigma-Aldrich

Pheniramine maleate salt

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About This Item

Formule empirique (notation de Hill):
C16H20N2 · C4H4O4
Numéro CAS:
132-20-7
Poids moléculaire :
356.42
Numéro CE :
205-051-4
Numéro MDL:
MFCD00079250
Code UNSPSC :
12352116
ID de substance PubChem :
24277769
Nomenclature NACRES :
NA.77

Forme

powder

Chaîne SMILES 

OC(=O)\C=C/C(O)=O.CN(C)CCC(c1ccccc1)c2ccccn2

InChI

1S/C16H20N2.C4H4O4/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16;5-3(6)1-2-4(7)8/h3-10,12,15H,11,13H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-

Clé InChI

SSOXZAQUVINQSA-BTJKTKAUSA-N

Informations sur le gène

human ... HRH1(3269)

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Actions biochimiques/physiologiques

Pheniramine maleate is a H1 histamine receptor antagonist. It is an alkylamine derivative. Structurally, pheniramine contains a chiral carbon atom with a hydrogen atom. Other substituents include the pyridyl, alkylamine and phenyl groups. It is used as an antiallergic drug for treating the common cold, respiratory allergies, urticaria, and systematic allergic reactions.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

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Ching-Hsia Hung et al.
European journal of pharmacology, 673(1-3), 20-24 (2011-11-03)
The aim of this study was to evaluate the local anesthetic effects of pheniramine and diphenhydramine, two histamine H₁ receptor antagonists, on spinal anesthesia and their comparison with lidocaine, a commonly used local anesthetic. After rats were injected intrathecally with
Ho Jun Lee et al.
Journal of Korean medical science, 24(5), 879-882 (2009-10-02)
The purpose of this study was to determine the effectiveness of antihistamine therapy for withdrawal movements caused by rocuronium injection. One hundred seventy one ASA I-II adults undergoing elective surgery were randomly assigned to one of two groups. Patients in
Tshering Lama et al.
Journal of telemedicine and telecare, 17(2), 105-108 (2010-12-09)
We describe a young woman from a rural village in Nepal who suffered multiple wasp and hornet stings. She collapsed and was managed by a telephone consultation between a village health worker and a hospital specialist. The patient recovered fully.
Ana B Guimaraes-Correa et al.
Viruses, 3(7), 1041-1058 (2011-10-14)
Adult T-cell leukemia/lymphoma (ATLL) is a highly aggressive disease that occurs in individuals infected with the human T lymphotropic virus type 1 (HTLV-1). Patients with aggressive ATLL have a poor prognosis because the leukemic cells are resistant to conventional chemotherapy.
Kerem Karaman et al.
American journal of surgery, 205(2), 213-219 (2012-09-05)
Laparoscopic cholecystectomy (LC) still leads to significant postoperative nausea and vomiting (PONV) and pain. Our aim was to evaluate the efficacy of dexamethasone or pheniramine hydrogen maleate, either alone or combined, in reducing the stress response and symptoms after LC.
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