C3025

(±)-Chlorpheniramine maleate salt

≥99% (perchloric acid titration)

• Formule empirique (notation de Hill): C₁₆H₁₉ClN₂ · C₄H₄O₄
• Numéro CAS: 113-92-8
• Poids moléculaire : 390.86
• Numéro CE : 204-037-5
• Numéro MDL: MFCD00069225
• Code UNSPSC : 12352116
• ID de substance PubChem : 24277767
• Nomenclature NACRES : NA.77

Propriétés

• Pureté: ≥99% (perchloric acid titration)
• Forme: powder
• Pf: 130-135 °C (lit.)
• Auteur: Bayer
• Chaîne SMILES: CN(C)CCC(C1=CC=C(Cl)C=C1)C2=NC=CC=C2.O=C(/C=C\C(O)=O)O
• InChI: 1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• Clé InChI: DBAKFASWICGISY-BTJKTKAUSA-N
• Informations sur le gène: human ... HRH1(3269)

Description

Description générale

Chlorpheniramine maleate (CPM)/(3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine is an alkylamine antihistamine.

Application

(±)-Chlorpheniramine maleate salt has been used:

• as H1 receptor antagonist to determine the receptor function
• to block the effect of compound 48/80 on plasma IGF-I
• as a standard for fast sensing and determination by sequential injector coupled with potentiometer

Actions biochimiques/physiologiques

Chlorpheniramine maleate (CPM) can prevent rhinitis and urticaria. It is used to cure several allergic conditions. This antihistamine is used in small-animal veterinary practices.

H₁ Histamine receptor antagonist.

Caractéristiques et avantages

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• Pictogrammes: GHS07
• Mention d'avertissement: Warning
• Mentions de danger: H302
• Conseils de prudence: P301 + P312 + P330
• Classification des risques: Acute Tox. 4 Oral
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges