The pH of a solution containing Poloxamer 188 may change over time due to factors such as hydrolysis or oxidation. The pH stability of Poloxamer 188 solutions has not been conducted. However, end users are encouraged to periodically monitor the solutions to ensure their stability and efficacy.
P5556
Poloxamer 188 solution
10%, sterile-filtered, BioReagent, suitable for insect cell culture
Synonyme(s) :
Nonionic copolymer surfactant
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100 ML
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100 ML
46,10 $
About This Item
Numéro CAS:
Numéro MDL:
Code UNSPSC :
12161902
ID de substance PubChem :
Nomenclature NACRES :
NA.75
Produits recommandés
Description
non-ionic
Stérilité
sterile-filtered
Gamme de produits
BioReagent
Poids mol.
average mol wt 8350
Concentration
10%
Technique(s)
cell culture | insect: suitable
Impuretés
endotoxin, tested
Température de transition
cloud point ≥100
HLB
29
Chaîne SMILES
O2C(C2)C.O1CC1
InChI
1S/C3H6O.C2H4O/c1-3-2-4-3;1-2-3-1/h3H,2H2,1H3;1-2H2
Clé InChI
RVGRUAULSDPKGF-UHFFFAOYSA-N
Description générale
Poloxamer 188 (P188) is a non-ionic amphiphilic copolymer. It comprises a central chain of hydrophobic polyoxypropylene flanked at ends by hydrophilic polyoxyethylene.[1]
Application
A nonionic copolymer surfactant
Actions biochimiques/physiologiques
Poloxamer 188 (P188) elicits hemorheological, antithrombotic, anti-inflammatory, and cytoprotective activities. It restores and stabilizes membrane barrier function. P188 also inhibits lipid peroxidation, reduces surface tension and hydrophobic-based cellular adherence.[1][2] P-188 exhibits low toxicity and may be used in oral drug delivery.
Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
WGK 2
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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How does the pH of the Poloxamer 188 solution fluctuate throughout a 24-month period?
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