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H6883

Sigma-Aldrich

3-(N,N-Dimethylpalmitylammonio)propanesulfonate

≥98% (TLC)

Synonyme(s) :

3-(N,N-Dimethylhexadecylammonio)propanesulfonate, 3-(Hexadecyldimethylammonio)propanesulfonate, 3-(Palmityldimethylammonio)propanesulfonate, Palmityl sulfobetaine, SB3-16

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About This Item

Formule linéaire :
CH3(CH2)15N+(CH3)2CH2CH2CH2SO3-
Numéro CAS:
2281-11-0
Poids moléculaire :
391.65
Numéro Beilstein :
4149854
Numéro CE :
218-918-7
Numéro MDL:
MFCD00036911
Code UNSPSC :
12161900
ID de substance PubChem :
24895773
Nomenclature NACRES :
NA.25

Description

zwitterionic

Pureté

≥98% (TLC)

Poids mol.

micellar avg mol wt 60,700

Nombre d'agrégation

155

Technique(s)

electrophoresis: suitable
mass spectrometry (MS): suitable
thin layer chromatography (TLC): suitable

Conductivité

≤10 μmho per cm at 24 °C (0.05 M aqueous solution)

CMC

0.01-0.06 mM (20-25°C)

Application(s)

cell analysis

Chaîne SMILES 

CCCCCCCCCCCCCCCC[N+](C)(C)CCCS([O-])(=O)=O

InChI

1S/C21H45NO3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22(2,3)20-18-21-26(23,24)25/h4-21H2,1-3H3

Clé InChI

TUBRCQBRKJXJEA-UHFFFAOYSA-N

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Catégories apparentées

Description générale

3-(N,N-Dimethylpalmitylammonio)propanesulfonate is a zwitterionic detergent.

Application

3-(N,N-Dimethylpalmitylammonio)propanesulfonate has been used in a study to assess the characterization of rat dihydroceramide desaturase. It has also been used in a study to investigate the inhibition of mitochondrial carnitine–acylcarnitine translocase by sulfobetaines. It is also used for extraction of proteins for analysis by chromatography, mass spectroscopy, and electrophoretic methods.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

230.0 °F - closed cup

Point d'éclair (°C)

110 °C - closed cup

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Sigma-Aldrich

00413

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(Lauryldimethylammonio)acetate ≥95% (HPLC)

Sigma-Aldrich

43781

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NDSB 211 ≥98% (TLC)

Sigma-Aldrich

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NDSB 211

R J Barry et al.
The Journal of biological chemistry, 264(16), 9231-9238 (1989-06-05)
Studies reported previously from this laboratory have demonstrated that membranes from the pigment epithelium of the vertebrate eye can transform free all-trans-retinol to 11-cis-retinol as well as 11-cis- and all trans-retinyl esters (Bernstein, P. S., Law, W. C., and Rando
H Erdjument-Bromage et al.
Journal of chromatography. A, 826(2), 167-181 (1999-01-01)
Mass spectrometry occupies a central position in most current protein identification schemes. So-called 'mass fingerprinting' techniques rely on composite mass patterns of proteolytic fragments, or dissociation products thereof, to query databases. Keys to successful analysis of ever smaller amounts are
R Parvin et al.
Canadian journal of biochemistry, 58(10), 822-830 (1980-10-01)
Sulfobetaines (N-alkyl-N,N-dimethyl-3-ammonio-1-propanesulfonates) have been identified as relatively specific and selective inhibitors of mitochondrial carnitine-acylcarnitine translocase. Thus, sublytic concentrations of sulfobetaines (alkyl = octyl to tetradecyl) inhibit the respiration of rat heart mitochondria supported by added acylcarnitines or pyruvate plus malonate
C Causeret et al.
Lipids, 35(10), 1117-1125 (2000-12-05)
The introduction of the double bond in the sphingoid backbone of sphingolipids occurs at the level of dihydroceramide via an NADPH-dependent desaturase, as discovered in permeabilized rat hepatocytes. In the rat, the enzyme activity, which has now been further characterized
M Lui et al.
Analytical biochemistry, 241(2), 156-166 (1996-10-15)
We have analyzed the efficacies of seven different organic solvents, 13 organic bases, and 17 detergents to dissociate electroblotted proteins from nitrocellulose. Most efficient were a 1% piperidine-40% acetonitrile mixture and 1% concentrations of either cetyltrimethylammonium bromide or several polyoxyethylene
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