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D8517

Sigma-Aldrich

Iron–Dextran

95-105 mg/mL (Iron content), solution

Synonyme(s) :

Ferric hydroxide dextran complex

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About This Item

Numéro CAS:
9004-66-4
Numéro MDL:
MFCD00081553
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25

Source biologique

synthetic

Niveau de qualité

200

Stérilité

aseptically filled

Pureté

95-105 mg/mL (Iron content)

Forme

solution

Contient

0.5% phenol as preservative

Composition

Iron, ~100 mg/mL

Couleur

brown

Plage de pH utile

4 - 6.5

Température de stockage

room temp

InChI

1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)

Clé InChI

MVZXTUSAYBWAAM-UHFFFAOYSA-N

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Application

Iron-Dextran (ferric hydroxide dextran complex) may be used as an intravenous iron delivery preparation. Iron-Dextran may be used to induce iron-overload to study its effects and preventative measures.

Autres remarques

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Danger

Mentions de danger

H317,H350

Classification des risques

Carc. 1B - Skin Sens. 1

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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S Fishbane et al.
Seminars in dialysis, 13(6), 381-384 (2000-12-29)
Intravenous iron treatment is an important component of anemia therapy for patients on dialysis. Until recently iron dextran was the only parenteral form of iron available in the United States. This drug has been associated with occasional serious adverse reactions
Laura Nigi et al.
Frontiers in endocrinology, 11, 630-630 (2020-10-13)
C-X-C Motif Chemokine Ligand 10 (CXCL10) is a pro-inflammatory chemokine specifically recognized by the ligand receptor CXCR3 which is mostly expressed in T-lymphocytes. Although CXCL10 expression and secretion have been widely associated to pancreatic islets both in non-obese diabetic (NOD)
Alejandro Martin-Malo et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 27(6), 2465-2471 (2011-12-31)
This study analysed, in vivo and in vitro, the effects of four different intravenous iron preparations (iron gluconate, iron sucrose, iron dextran and ferric carboxymaltose) on activation and damage of mononuclear cells. A randomized prospective study was conducted in 10
Xiao Chai et al.
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 35(5), 547-552 (2013-11-05)
To establish a mouse model of iron overload by intraperitoneal injection of iron dextran and investigate the impact of iron overload on bone marrow hematopoiesis. A total of 40 C57BL/6 mice were divided into control group, low-dose iron group (12.5
Zachariah DeFilipp et al.
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 9(1), 129-132 (2012-08-08)
Iron deficiency is a major postoperative complication of Roux-en-Y gastric bypass surgery. Oral replacement can fail to correct the deficiency. Thus, recourse to parenteral iron administration might be necessary. Our objective was to evaluate the effectiveness and safety of a
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