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Principaux documents

C4431

Sigma-Aldrich

Citrate-phosphate-dextrose solution with adenine

Synonyme(s) :

CPD-A

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About This Item

Code UNSPSC :
12161700
Nomenclature NACRES :
NA.25
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Stérilité

sterile-filtered

Niveau de qualité

200

Forme

liquid

pH

5.4-6.7

Température de stockage

2-8°C

Catégories apparentées

Description générale

Citrate-phosphate-dextrose solution with adenine (CPDA) is an anticoagulant and preservative for storage of blood. It can prolong red blood cell storage life up to 35 days. It maintains platelet viability.[1] Usage of CPDA improves post-transfusion visibility and improves glucose and ATP levels in blood.[2]

Application

Citrate-phosphate-dextrose solution with adenine has been used as an anticoagulant during blood collection from cardiac puncture,[3] transgenic hen egg lysozyme-ovalbumin-Duffy (HOD) mice[4] and humans.[5]

Actions biochimiques/physiologiques

Useful anticoagulant for whole blood
Recommended anticoagulant: whole blood ratio is 1:9

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

08168

Timestrip Plus™ 8 °C

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
0000421395
0000421395
0000387191
0000346907
0000362204

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Acide citrique ACS reagent, ≥99.5%

Sigma-Aldrich

251275

Acide citrique

HyunJoo Park et al.
Scientific reports, 6, 34257-34257 (2016-10-05)
The functionality and viability of stored human red blood cells (RBCs) is an important clinical issue in transfusions. To systematically investigate changes in stored whole blood, the hematological properties of individual RBCs were quantified in blood samples stored for various
Krishnan MohanKumar et al.
Nature communications, 10(1), 3494-3494 (2019-08-04)
Necrotizing enterocolitis (NEC) is an idiopathic, inflammatory bowel necrosis of premature infants. Clinical studies have linked NEC with antecedent red blood cell (RBC) transfusions, but the underlying mechanisms are unclear. Here we report a neonatal murine model to investigate this
James C Keith et al.
Arthritis research & therapy, 7(4), R769-R776 (2005-07-01)
The human leukocyte antigen B27 (HLA-B27) transgenic rat is a model of human inflammatory bowel disease, rheumatoid arthritis and psoriasis. Studies of chronic inflammation in other rat models have demonstrated activation of the kallikrein-kinin system as well as modulation by
Taesik Go et al.
Scientific reports, 10(1), 8977-8977 (2020-06-04)
Digital holographic microscopy enables the recording of sample holograms which contain 3D volumetric information. However, additional optical elements, such as partially or fully coherent light source and a pinhole, are required to induce diffraction and interference. Here, we present a
A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat
Keith JC, et al.
Arthritis Research & Therapy, 7(4), R769-R769 (2005)
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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