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B6295

Sigma-Aldrich

Chlorure de benzalkonium

BioXtra

Synonyme(s) :

Chlorure d'alkylbenzyldiméthylammonium, Chlorure d'alkyldiméthylbenzylammonium

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154,00 $
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593,00 $

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100 G
154,00 $
500 G
593,00 $

About This Item

Formule linéaire :
C6H5CH2N(CH3)2RCl (R=C8H17 to C18H37)
Numéro CAS:
63449-41-2
Beilstein:
4062599
Numéro CE :
264-151-6
Numéro MDL:
MFCD00145757
Code UNSPSC :
12161900
ID de substance PubChem :
24891904
Nomenclature NACRES :
NA.25

154,00 $

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Description

cationic

Gamme de produits

BioXtra

Essai

95.0-105.0% (calculated on dry substance)

Forme

(Solid or Semi-Solid or Viscous Liquid)

Impuretés

≤0.001% Phosphate
≤0.1% Insoluble matter
≤10% water

Résidus de calcination

≤2%

Traces d'anions

sulfate (SO42-): ≤0.05%

Traces de cations

Al: ≤0.0005%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
Na: ≤0.02%
Pb: ≤0.001%
Zn: ≤0.0005%

Chaîne SMILES 

[Cl-].CCCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1

InChI

1S/C19H34N.ClH/c1-4-5-6-7-8-9-10-14-17-20(2,3)18-19-15-12-11-13-16-19;/h11-13,15-16H,4-10,14,17-18H2,1-3H3;1H/q+1;/p-1

Clé InChI

TTZLKXKJIMOHHG-UHFFFAOYSA-M

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Catégories apparentées

Description générale

Benzalkonium chloride is a cationic detergent that is a member of quaternary ammonium compounds (QACs). [1]

Application

Benzalkonium chloride has been used in a study to assess its action on epithelia conjunctival cells in vitro. [2] It has also been used in a study to investigate its effects on living rabbit cornea by in vivo Tandem scanning confocal microscopy. [3]

Clause de non-responsabilité

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Pictogrammes

CorrosionExclamation markEnvironment
GHS05,GHS07,GHS09

Mention d'avertissement

Danger

Mentions de danger

H302 + H312,H314,H410

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B

Code de la classe de stockage

8B - Non-combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificats d'analyse (COA)

Lot/Batch Number
BCCM6787
BCCM3161
BCCL5308
BCCK7584
BCCK6479

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

M De Saint Jean et al.
Investigative ophthalmology & visual science, 40(3), 619-630 (1999-03-06)
The aim of this study was to investigate the action of benzalkonium chloride (BAC), used as a preservative in most ophthalmic topical solutions, on epithelial conjunctival cells in vitro. A continuous human conjunctival cell line (Wong-Kilbourne derivative of Chang conjunctiva)
H Ichijima et al.
Cornea, 11(3), 221-225 (1992-05-01)
The effects of benzalkonium chloride (BAK) on the living rabbit cornea were studied by in vivo Tandem scanning confocal microscopy (TSCM) and confirmed by conventional scanning electron microscopy (SEM). Two drops of saline or phosphate-buffered saline (PBS) containing BAK in
Céline Portal et al.
PloS one, 12(3), e0174764-e0174764 (2017-03-30)
Modification of mucous cell density and gel-forming mucin production are established hallmarks of mucosal diseases. Our aim was to develop and validate a mouse model to study live goblet cell density in pathological situations and under pharmacological treatments. We created
Dana Cervinkova et al.
Microbial drug resistance (Larchmont, N.Y.), 19(3), 160-167 (2012-12-22)
Conditions facilitating resistance to quaternary ammonium compounds (QACs) were investigated in Staphylococcus aureus SK982 exposed to benzalkonium chloride (BAC; a member of QACs) under various circumstances. S. aureus SK982 carrying the qacA gene encoding for resistance to QACs was grown
Eric G Romanowski et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 35(5), 311-314 (2019-04-11)
Purpose: Adenoviral conjunctivitis is the most common cause of conjunctivitis worldwide with no approved antiviral treatment. Benzalkonium chloride (BAK)
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Questions

1–5 of 5 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Benzalkonium chloride을 검색해봤을때 물에 잘 녹는다 나옵니다. 귀사에서 제공하는 SDS에는 물에 안녹는다나와있는데 확인된 정보가 맞을까요?

    1 answer

    1. Benzalkonium chloride is soluble in water. According to the Safety Data Sheet, moisture should be avoided with benzalkonium chloride as it can cause stability issues for the unused product.

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  4. What is the solubility?

    1 answer

    1. There are no specific solubility assays that are performed on this product. This is a very water-soluble compound.

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  5. Bjr, quelle est la durée possible d'utilisation d'un standard (cas du produit 12060, date de release 28/06/2023, lot BCCK4742) : +2 ans?, +3 ans..

    1 answer

    1. This product is not assigned an expiration date. It is assigned a recommended retest date of approximately 2 years after the quality release date. A recommended retest date is the time during which the product is expected to remain within established stability specifications, provided that it has been stored under defined conditions. After the Retest Date, product samples should be examined to ensure that the product is still in compliance with the established specifications.

      For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services.

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