A4486
AMPK (α1/β1/γ3), active, His tagged human
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Synonyme(s) :
HAMPKb, MGC17785, MGC33776, MGC57364, PRKAA1, PRKAB1, PRKAG3
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A propos de cet article
NACRES:
NA.77
UNSPSC Code:
12352200
Specific activity:
157-213 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells
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Laissez-nous vous aiderrecombinant
expressed in baculovirus infected Sf9 cells
Quality Segment
product line
PRECISIO® Kinase
assay
≥70% (SDS-PAGE)
form
buffered aqueous glycerol solution
specific activity
157-213 nmol/min·mg
mol wt
A1 subunit ~68 kDa, B1 subunit ~38 kDa, G3 subunit ~51 kDa
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... PRKAA1(5562), PRKAB1(5564), PRKAG3(53632)
Biochem/physiol Actions
AMPK (A1/B1/G3) is a member of the AMPK family which are heterotrimeric proteins consisting of an α catalytic subunit, and non-catalytic β and γ subunits. AMPKs are an important energy-sensing enzyme group in the cells that monitor energy status particularly in response to stress. AMPKs regulate fatty acid and cholesterol synthesis by regulating the key rate-limiting enzymes acetyl-CoA carboxylase and 3-hydroxy-3-methylglutaryl-CoA reductase. The γ subunit is dominantly expressed in skeletal muscle where it may play a key role in the regulation of energy metabolism.
Physical form
Supplied in 50 mM Sodium Phosphate, pH 7.0, with 150 mM imidazole, 0.1 mM PMSF, 0.2 mM DTT, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Repr. 1B
Classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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