PRKAG3
protein kinase, AMP-activated, gamma 3 non-catalytic subunit
Synonyms:
AMPKG3
Species:
Human PRKAG3 (53632), Mouse Prkag3 (241113), Rat Prkag3 (301518), cow PRKAG3 (511961), domestic guinea pig Prkag3 (100724729), chicken PRKAG3 (424208), naked mole-rat Prkag3 (101699667), Domestic Rabbit PRKAG3 (100352581), domestic cat PRKAG3 (101092204), sheep PRKAG3 (100142674) ...More
UniProtKB ID:
Gene ID:
- Human(53632) Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq, Jul 2008]
- Mouse(241113) protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
- Rat(301518) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
- cow(511961) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
- domestic guinea pig(100724729) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
- chicken(424208) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
- naked mole-rat(101699667) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
- Domestic Rabbit(100352581) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
- domestic cat(101092204) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
- sheep(100142674) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
- Goat(100861301) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
- Horse(100034099) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
- dog(488526) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
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Proteins
Product Number
Description
Species
AMPK (α1/β1/γ3), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human