Accéder au contenu
MilliporeSigma
Toutes les photos(1)

Documents

A3145

Sigma-Aldrich

Apigenin

≥97% (TLC), from parsley, powder

Synonyme(s) :

4′,5,7-Trihydroxyflavone, 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme
Toutes les photos(1)

About This Item

Formule empirique (notation de Hill):
C15H10O5
Numéro CAS:
520-36-5
Poids moléculaire :
270.24
Numéro Beilstein :
262620
Numéro CE :
208-292-3
Numéro MDL:
MFCD00006831
Code UNSPSC :
12352200
ID de substance PubChem :
24278212

Source biologique

parsley

Pureté

≥97% (TLC)

Forme

powder

Couleur

yellow

Pf

>300 °C (lit.)

Solubilité

DMSO: 27 mg/mL
1 M KOH: 50 mg/mL

Température de stockage

−20°C

Chaîne SMILES 

Oc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2

InChI

1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H

Clé InChI

KZNIFHPLKGYRTM-UHFFFAOYSA-N

Informations sur le gène

human ... ADORA3(140) , CDC2(983) , CDK5(1020) , CDK6(1021) , CYP1A2(1544) , ESR1(2099) , ESR2(2100) , GSK3A(2931)
mouse ... Hexa(15211)
rat ... Adora1(29290) , Adora2a(25369) , Il4(287287) , Tnf(24835)

Vous recherchez des produits similaires ? Visite Guide de comparaison des produits

Actions biochimiques/physiologiques

A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Les clients ont également consulté

Slide 1 of 5

1 of 5

Kaempferol ≥90% (HPLC), powder

Sigma-Aldrich

K0133

Kaempferol

Daidzein ≥98%, synthetic

Sigma-Aldrich

D7802

Daidzein

(±)-Naringenin ≥95%

Sigma-Aldrich

N5893

(±)-Naringenin

Quercetin ≥95% (HPLC), solid

Sigma-Aldrich

Q4951

Quercetin

Chlorogenic acid ≥95% (titration)

Sigma-Aldrich

C3878

Chlorogenic acid

Émilie C Lefort et al.
Molecular nutrition & food research, 57(1), 126-144 (2012-12-01)
Apigenin (4',5,7-trihydroxyflavone, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) is a flavonoid found in many fruits, vegetables, and herbs, the most abundant sources being the leafy herb parsley and dried flowers of chamomile. Present in dietary sources as a glycoside, it is cleaved in the gastrointestinal
Naiara Silva Dourado et al.
Frontiers in aging neuroscience, 12, 119-119 (2020-06-06)
Neurodegenerative disorders (ND) are characterized by the progressive and irreversible loss of neurons. Alzheimer's Disease (AD) is the most incident age-related ND, in which the presence of a chronic inflammatory compound seems to be related to its pathogenesis. Different stimuli
Benjamin Dilberger et al.
Nutrients, 11(8) (2019-08-16)
(1) Background: Polyphenols (PP) play an important role in the prevention of non-communicable diseases and may contribute to healthy aging. To investigate the molecular and cellular aspects of PP metabolites on longevity with a focus on mitochondrial function, we applied
John Sanseverino et al.
Toxicological sciences : an official journal of the Society of Toxicology, 107(1), 122-134 (2008-11-11)
Saccharomyces cerevisiae bioluminescent bioreporter assays were developed previously to assess a chemical's estrogenic or androgenic disrupting potential. S. cerevisiae BLYES, S. cerevisiae BLYAS, S. cerevisiae BLYR, were used to assess their reproducibility and utility in screening 68, 69, and 71
Kaihui Lu et al.
Journal of natural products, 76(4), 672-678 (2013-03-26)
Adipocyte dysfunction is a major cause of obesity, which is associated strongly with many disorders including psychological and medical morbidities, metabolic abnormalities, and cardiovascular diseases as well as a series of cancers. This study investigated the antiadipogenic activity of scutellarin
Afficher tous les articles scientifiques apparentés

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique