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Y0001046

Sevoflurane

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane

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About This Item

Formule empirique (notation de Hill):
C4H3F7O
Numéro CAS:
28523-86-6
Poids moléculaire :
200.05
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

sevoflurane

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

InChI

1S/C4H3F7O/c5-1-12-2(3(6,7)8)4(9,10)11/h2H,1H2

Clé InChI

DFEYYRMXOJXZRJ-UHFFFAOYSA-N

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sevoflurane EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H315,H319

Classification des risques

Eye Irrit. 2 - Skin Irrit. 2

Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number

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1,1,1,3,3,3-Hexafluoro-2-propanol United States Pharmacopeia (USP) Reference Standard

USP

1612594

1,1,1,3,3,3-Hexafluoro-2-propanol

USP

USP

1349003

Isoflurane

Dexmedetomidine hydrochloride ≥98% (HPLC)

Sigma-Aldrich

SML0956

Dexmedetomidine hydrochloride

Tetramethylammonium fluoride 97%

Sigma-Aldrich

459135

Tetramethylammonium fluoride

Joachim Erb et al.
The Journal of international medical research, 42(3), 750-764 (2014-05-02)
Levosimendan is an inotropic drug with organ-protective properties due to its activation of mitochondrial K(ATP) channels. This prospective, randomized, double-blind, placebo-controlled study investigated whether administration of levosimendan prior to cardiopulmonary bypass could reduce organ dysfunction and influence subsequent secondary endpoints.
Norifumi Kuratani et al.
Anesthesiology, 109(2), 225-232 (2008-07-24)
Sevoflurane is a popular inhalational anesthetic for general anesthesia in children. The higher incidence of emergence agitation has been suspected after sevoflurane anesthesia as compared with halothane, whereas some controlled studies showed conflicting results. In this report, the authors performed
Maj-Lis Lindholm et al.
Anesthesia and analgesia, 118(4), 782-787 (2014-03-22)
Preclinical data indicate that anesthesia and surgery may promote cancer growth. We previously found no increased risk of malignant disease within 5 years regarding duration of general anesthesia (TANESTH) and time with Bispectral Index (BIS) under 45 (TBIS < 45)
Jan Kehler et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 55(9), 1513-1518 (2014-07-06)
Phosphodiesterase 10A (PDE10A) plays a key role in the regulation of brain striatal signaling, and several pharmaceutical companies currently investigate PDE10A inhibitors in clinical trials for various central nervous system diseases. A PDE10A PET ligand may provide evidence that a
G Landoni et al.
British journal of anaesthesia, 111(6), 886-896 (2013-07-16)
Many studies have compared desflurane, isoflurane, sevoflurane, total i.v. anaesthesia (TIVA), or all in cardiac surgery to assess their effects on patient survival. We performed standard pairwise and Bayesian network meta-analyses; the latter allows indirect assessments if any of the
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