Y0000227
Meso-rich exametazime
European Pharmacopoeia (EP) Reference Standard
Synonyme(s) :
Exametazime
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About This Item
Formule empirique (notation de Hill):
C13H28N4O2
Numéro CAS:
Poids moléculaire :
272.39
Code UNSPSC :
41116107
Nomenclature NACRES :
NA.24
Produits recommandés
Qualité
pharmaceutical primary standard
Famille d'API
meso-rich exametazime
Fabricant/nom de marque
EDQM
Application(s)
pharmaceutical (small molecule)
Format
neat
Température de stockage
2-8°C
InChI
1S/C13H28N4O2/c1-9(11(3)16-18)14-7-13(5,6)8-15-10(2)12(4)17-19/h9-10,14-15,18-19H,7-8H2,1-6H3/b16-11+,17-12+/t9-,10-/m1/s1
Clé InChI
BPNZYADGDZPRTK-UDUYQYQQSA-N
Description générale
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Meso-rich exametazime EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Conditionnement
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Autres remarques
Sales restrictions may apply.
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C Solanki et al.
Nuclear medicine communications, 19(6), 567-572 (1999-05-11)
The objective of this study was to increase the stability of 99Tcm-exametazime and to investigate the effects of relaxing the eluate restrictions imposed by the manufacturer. We added 1800 MBq freshly eluted pertechnetate to 0.5 ml aliquots of stannous-enhanced exametazime
D Vanderghinste et al.
Journal of pharmaceutical and biomedical analysis, 32(4-5), 679-685 (2003-08-06)
99mTc-exametazime (99mTc-d,l-HMPAO, 99mTc-d,l-hexamethylpropyleneamine oxime) is a neutral rather unstable complex of short-lived 99mTc (t(1/2)=6 h) with the d,l-isomer (mixture of D,D- and L,L-isomers) of a bis-amine bis-oxime tetraligand. It is widely used for measurement of regional cerebral perfusion in nuclear
N Nikolić et al.
Journal of pharmaceutical and biomedical analysis, 32(6), 1159-1166 (2003-08-09)
The diastereo-enantio separation of isomeric mixtures of exametazime (HM-PAO) by liquid chromatography is described using an achiral sorbent (RP-18). A chiral eluent with the initial complex of Cu(II) and the optically active selector N,N-dimethyl-l-phenylalanine (l-DM-PhA), based on the ligand-exchange principle
G Sambuceti et al.
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of..., 57(2), 207-215 (2013-07-05)
Despite its enormous relevance, homing of hematopoietic stem cells (SCs) remains relatively uncertain due to the limitations of measuring small number of systemically administered cells in the different organs. Despite its high sensitivity, radionuclide detection has been relatively underutilized to
Pierre-Yves Litzler et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 51(7), 1044-1048 (2010-06-18)
We report our experience with using integrated molecular and anatomic hybrid imaging to assess infection in patients who have a left-ventricular-assist device (LVAD). Thirteen (99m)Tc-exametazime-leukocyte planar and SPECT/CT scans were obtained for 8 consecutive patients who had an implanted LVAD.
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