Dihydrodaidzein is an active metabolite of daidzein. It has vasodilatory action on rat isolated aortic rings. It stimulates the estrogen receptor-dependent growth of breast cancer MCF-7 cells at micromolar concentrations. Dihydrodaidzein is produced by the metabolism of daidzein in colonic bacteria and may be further metabolized to various bioactive compounds, including equol .Outside of the human body, Dihydrodaidzein has been detected in several different foods, such as cloves, agars, ohelo berries, greenthread tea, and mexican groundcherries. This could make dihydrodaidzein a potential biomarker for the consumption of these foods.
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Metabolomics research
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