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N1200000

19-Norethindrone

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

17-hydroxy-19-nor-17α-4-pregnène-20-yn-3-one, 17α-éthynyl-17β-hydroxy-19-nor-4-androstène-3-one, 17α-éthynyl-19-nortestostérone, 19-nor-17α-éthynyl-4-androstène-17β-ol-3-one

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25 MG
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About This Item

Formule empirique (notation de Hill) :
C20H26O2
Numéro CAS:
Poids moléculaire :
298.42
Beilstein:
1915671
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

205,00 $


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Devis pour commande en gros

Qualité

pharmaceutical primary standard

Famille d'API

norethisterone

Fabricant/nom de marque

EDQM

Pf

205-206 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

[H][C@]12CCC(=O)C=C1CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4(O)C#C

InChI

1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,12,15-18,22H,4-11H2,2H3/t15-,16+,17+,18-,19-,20-/m0/s1

Clé InChI

VIKNJXKGJWUCNN-XGXHKTLJSA-N

Informations sur le gène

human ... PGR(5241)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Norethisterone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Actions biochimiques/physiologiques

19-norethindrone is an oral contraceptive involved in the inhibition of cytosolic sulfotransferases (SULT).

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Pictogrammes

Health hazardEnvironment

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3


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Les clients ont également consulté

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Derin J Cobia et al.
Schizophrenia research, 139(1-3), 1-6 (2012-06-01)
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Patricia M LoRusso et al.
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Vismodegib, a first-in-class oral hedgehog pathway inhibitor, is an effective treatment for advanced basal cell carcinoma. Based on in vitro data, a clinical drug-drug interaction (DDI) assessment of cytochrome P450 (CYP) 2C8 was necessary; vismodegib's teratogenic potential warranted a DDI
H F Taitel et al.
International journal of fertility and menopausal studies, 40(4), 207-223 (1995-07-01)
Norethindrone is utilized for numerous noncontraceptive therapies, especially during the menopause. Through an analysis of the literature we have described the pharmacological profile of norethindrone and the potential therapeutic implications of low-dose therapies, with an emphasis on endometrial pathology, climacteric
P Vercellini et al.
Human reproduction (Oxford, England), 27(12), 3450-3459 (2012-08-29)
Does surgical or medical treatment for endometriosis-associated severe deep dyspareunia achieve better results in terms of patients' satisfaction (main study outcome), variation of coital pain and frequency of intercourse? Surgery and progestin therapy were equally effective in the treatment of
Karl van den Broeck et al.
The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception, 17(5), 321-328 (2012-09-15)
Ferdinand Peeters, a practising gynaecologist from Turnhout, near Antwerp (Belgium), had a pivotal role in the development of a practical and viable modality of oral contraception, striking the balance between efficacy and an acceptably low incidence and severity of side

Questions

  1. What's the dissolvant of this Norethisterone besides DMSO?

    1 answer
    1. This product is a Reference Standard supplied by the European Pharmacopoeia (EP). The solubility of this product is provided. The identical compound is also available as a research grade product, N4124, which is tested for solubility at 50 mg/mL in Chloroform. Additional solvents referenced in available literature are ethanol, methanol, and acetonitrile, as well as other organic solvents.

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