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F8639

Supelco

Famprofazone

analytical standard

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About This Item

Formule empirique (notation de Hill):
C24H31N3O
Numéro CAS:
Poids moléculaire :
377.52
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

Chaîne SMILES 

CC(C)C1=C(CN(C)C(C)Cc2ccccc2)N(C)N(c3ccccc3)C1=O

InChI

1S/C24H31N3O/c1-18(2)23-22(17-25(4)19(3)16-20-12-8-6-9-13-20)26(5)27(24(23)28)21-14-10-7-11-15-21/h6-15,18-19H,16-17H2,1-5H3

Clé InChI

GNUXVOXXWGNPIV-UHFFFAOYSA-N

Description générale

Famprofazone is a pyrazole derivative[1] and belongs to the class of non-steroidal anti-inflammatory drugs.[2] It is widely used as an analgesic and antipyretic in medical applications.[3][4]

Application

Famprofazone may be used as an analytical reference standard for the quantification of the analyte in biological samples using liquid chromatography coupled to tandem mass spectrometry.[5]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves


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Certificats d'analyse (COA)

Lot/Batch Number

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J T Cody
Forensic science international, 80(3), 189-199 (1996-07-12)
Fourteen different metabolic precursors of amphetamine or methamphetamine have previously been identified. Many of these drugs are available only by prescription and several are only available in some parts of the world and not in others. One of these drugs
E S Oh et al.
Xenobiotica; the fate of foreign compounds in biological systems, 22(3), 377-384 (1992-03-01)
1. To obtain further evidence for the metabolic formation of methamphetamine from famprofazone in man, concentrations of methamphetamine in plasma, as well as in urine, were measured by g.l.c. In addition, intact famprofazone and famprofazone N-oxide were analysed in the
Identification of new urinary metabolites of famprofazone in humans
Journal of Analytical Toxicology, 22(1), 55-60 (1998)
F Musshoff
Drug metabolism reviews, 32(1), 15-44 (2000-03-11)
The interpretation of methamphetamine and amphetamine positive test results in biological samples is a challenge to clinical and forensic toxicology for several reasons. The effects of pH and dilution of urine samples and the knowledge about legitimate and illicit sources
Ying Lung Tseng et al.
Journal of forensic sciences, 52(2), 479-486 (2007-02-24)
During a sport competition event in Taiwan, one urine specimen was found positive for both methamphetamine (2688 ng/mL) and amphetamine (462 ng/mL). The specimen donor claimed that she had taken Gewolen (a nonprescription drug manufactured in Taiwan) for treating abdominal

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