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Oxyclozanide

VETRANAL®, analytical standard

Synonyme(s) :

2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide, 3,3′,5,5′,6-Pentachloro-2′-hydroxysalicylanilide

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About This Item

Formule empirique (notation de Hill):
C13H6Cl5NO3
Numéro CAS:
2277-92-1
Poids moléculaire :
401.46
Numéro CE :
218-904-0
Numéro MDL:
MFCD00864507
Code UNSPSC :
41116107
ID de substance PubChem :
329754798
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

100

Gamme de produits

VETRANAL®

Durée de conservation

limited shelf life, expiry date on the label

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

Chaîne SMILES 

Oc1c(Cl)cc(Cl)cc1NC(=O)c2c(O)c(Cl)cc(Cl)c2Cl

InChI

1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22)

Clé InChI

JYWIYHUXVMAGLG-UHFFFAOYSA-N

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Description générale

Oxyclozanide is an anthelmintic agent, which can show activity against Fasciola hepatica, a parasitic trematode and hence, can be used in the treatment of liver fluke infections.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informations légales

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Exclamation markEnvironment
GHS07,GHS09

Mention d'avertissement

Warning

Mentions de danger

H302,H410

Classification des risques

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
BCCK0517
BCCJ3689
BCCD2132
BCCC1795
BCBV2215

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Sigma-Aldrich

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S A Spence et al.
Australian veterinary journal, 69(9), 217-220 (1992-09-01)
A significant increase in milk production, averaging 164 litres per cow per lactation (a 4.8% increase), was seen after cows infected with gastrointestinal nematodes, paramphistomes and Fasciola hepatica were treated with broad-spectrum anthelmintics. Three hundred and ninety pairs of cows
E E Guobadia et al.
Veterinary parasitology, 68(3), 269-282 (1997-02-01)
The 17kDa and 69kDa polypeptide antigens which are specific to Fasciola gigantica were excised from polyacrylamide gels and used for the immunization of rabbits to raise monospecific antisera against these polypeptides. These sera were labelled with horseradish peroxidase and used
C Paraud et al.
Veterinary journal (London, England : 1997), 180(2), 265-267 (2008-03-04)
Paramphistome infections are very common in ruminants and may induce clinical signs, but little is known about effective treatments. In this study, the efficacy of oxyclozanide against Calicophoron daubneyi was studied in goats and its activity tested against immature stages
Treatment of Dicrocoelium dendriticum with a combination of thiophanate and brotianide.
B Tinar et al.
The Veterinary record, 123(25), 650-651 (1988-12-17)
I Bremner et al.
The Veterinary record, 123(9), 217-218 (1988-08-27)
The benefits of the inclusion of cobalt and selenium supplements in anthelmintic preparations were demonstrated in a 10 week trial with cobalt- and selenium-deficient blackface wethers. The anthelmintics were based on oxfendazole and on levamisole plus oxyclozanide; three doses provided
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