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Sigma-Aldrich

Cysteamine hydrochloride

≥97.0% (RT)

Synonyme(s) :

β-Mercapto­ethylamine hydrochloride, 2-Amino­ethane­thiol hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, Decarboxy­cysteine hydrochloride, Thio­ethanol­amine hydrochloride

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About This Item

Formule linéaire :
HSCH2CH2NH2 · HCl
Numéro CAS:
156-57-0
Poids moléculaire :
113.61
Numéro Beilstein :
3590083
Numéro CE :
205-858-1
Numéro MDL:
MFCD00012904
Code UNSPSC :
41106305
ID de substance PubChem :
329753425
Nomenclature NACRES :
NA.51

Niveau de qualité

200

Pureté

≥97.0% (RT)

Forme

crystals

Pf

64-70 °C
67-71 °C

Température de stockage

2-8°C

Chaîne SMILES 

Cl[H].NCCS

InChI

1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H

Clé InChI

OGMADIBCHLQMIP-UHFFFAOYSA-N

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Application

Cysteamine hydrochloride has been used in the in-situ generation of chiral cysteamine-capped cadmium sulfide quantum dots (CA-CdS QDs) for the sensing of Cd2+ and S2-.

Actions biochimiques/physiologiques

Cysteamine hydrochloride is derived from the degradation of coenzyme A endogenously. Its concentration in plasma is low. It is commonly used as a drug for the orphan disease cystinosis, a lysosomal storage disorder, in which cysteamine decreases intralysosomal cystine accumulation.
Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine. Cysteamine is used in a wide range of applications from regulation of gene expression, to depletion of somatostatin, to coating of nanoparticles.

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302,H317,H319,H335

Classification des risques

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Gloves

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Certificats d'analyse (COA)

Lot/Batch Number
BCCL6109
BCCM1451
BCCK2275
BCCH7252
BCCG0901

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Consulter la Bibliothèque de documents

A circular dichroism sensor for selective detection of Cd2+ and S2- based on the in-situ generation of chiral CdS quantum dots
Sianglam P, et al.
Spectrochemical Analysis by Atomic Absorption and Emission, 183, 408-416 (2017)
Martine Besouw et al.
Drug discovery today, 18(15-16), 785-792 (2013-02-19)
Cysteamine is an amino thiol with the chemical formula HSCH2CH2NH2. Endogenously, cysteamine is derived from coenzyme A degradation, although its plasma concentrations are low. Most experience with cysteamine as a drug originates from the field of the orphan disease cystinosis
Mengxiao Yu et al.
Journal of the American Chemical Society, 133(29), 11014-11017 (2011-07-01)
pH regulates many cellular processes and is also an indicator of disease progression. Therefore, pH-responsive materials often serve as either tools in the fundamental understanding of cell biology or medicine for disease diagnosis and therapy. While gold nanoparticles have broad
Nida Zaman Khan et al.
ACS omega, 6(40), 25926-25939 (2021-10-19)
Heparin-induced thrombocytopenia (HIT) antibodies (Abs) can mediate and activate blood cells, forming blood clots. To detect HIT Abs, immunological assays with high sensitivity (≥95%) and fast response are widely used, but only about 50% of these tests are accurate as
Rajib Ghosh et al.
Biomaterials, 34(3), 807-816 (2012-11-01)
Lack of affordable technologies for delivering microRNAs and siRNAs into cells on a large scale has hindered our efforts to rapidly parse through hundreds of dysregulated genes/microRNAs in order to identify drivers of complex diseases. The instability and polyanionic nature
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