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36-009

Sigma-Aldrich

Anti-β-Synuclein Antibody, clone Syn207

ascites fluid, clone Syn207, Upstate®

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

mouse

Niveau de qualité

Forme d'anticorps

ascites fluid

Type de produit anticorps

primary antibodies

Clone

Syn207, monoclonal

Espèces réactives

rat, mouse, human

Fabricant/nom de marque

Upstate®

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... SNCB(6620)

Spécificité

recombinant β-Synuclein

Immunogène

full length recombinant human β-Synuclein

Application

Anti-β-Synuclein Antibody, clone Syn207 is an antibody against β-Synuclein for use in WB, IH.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Qualité

routinely evaluated by immunoblot lot detected β-Synuclein recombinant protein

Description de la cible

~17kDa

Forme physique

Ascites
ascites with 0.05% sodium azide

Stockage et stabilité

2 years at -20°C

Informations légales

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1


Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

P H Tu et al.
Annals of neurology, 44(3), 415-422 (1998-09-28)
Recently, alpha-synuclein was shown to be a structural component of the filaments in Lewy bodies (LBs) of Parkinson's disease (PD), dementia with LBs (DLB) as well as the LB variant of Alzheimer's disease, and this suggests that alpha-synuclein could play
Emmy H Rannikko et al.
BMC neuroscience, 16, 57-57 (2015-09-09)
The pathological hallmarks of Parkinson's disease are intracellular inclusions composed mainly of misfolded α-synuclein (αSYN). Under physiological conditions αSYN is mostly localized in synapses. In addition, a portion of αSYN is secreted to the extracellular space, where it may be
B I Giasson et al.
Journal of neuroscience research, 59(4), 528-533 (2000-02-19)
To facilitate studies of the normal biology of alpha-synuclein, a member of a family of neuronal proteins of unknown function, and to elucidate the role of alpha-synuclein pathologies in neurodegenerative diseases, we generated and characterized a panel of anti-synuclein antibodies.
Development of new treatments for Parkinson's disease in transgenic animal models: a role for beta-synuclein.
Masliah, Eliezer and Hashimoto, Makoto
Neurotoxicology, 23, 461-468 (2002)
Suna Lahut et al.
Disease models & mechanisms, 10(5), 619-631 (2017-01-22)
Parkinson's disease (PD) is a frequent neurodegenerative process in old age. Accumulation and aggregation of the lipid-binding SNARE complex component α-synuclein (SNCA) underlies this vulnerability and defines stages of disease progression. Determinants of SNCA levels and mechanisms of SNCA neurotoxicity

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