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TOR-Dependent and -Independent Pathways Regulate Autophagy in

Frontiers in plant science (2017-07-27)
Yunting Pu, Xinjuan Luo, Diane C Bassham
RESUMO

Autophagy is a critical process for recycling of cytoplasmic materials during environmental stress, senescence and cellular remodeling. It is upregulated under a wide range of abiotic stress conditions and is important for stress tolerance. Autophagy is repressed by the protein kinase target of rapamycin (TOR), which is activated in response to nutrients and in turn upregulates cell growth and translation and inhibits autophagy. Down-regulation of TOR in

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Triton X-100, laboratory grade
Sigma-Aldrich
Membrane Scaffold Protein 1E3D1 D73C, recombinant, expressed in E. coli, Cysteine substituted at position 73