- A new general access to either type of Securinega alkaloids: synthesis of securinine and (-)-allonorsecurinine.
A new general access to either type of Securinega alkaloids: synthesis of securinine and (-)-allonorsecurinine.
Organic letters (2004-05-21)
Ramon Alibés, Marta Ballbé, Félix Busqué, Pedro de March, Laia Elias, Marta Figueredo, Josep Font
PMID15151421
RESUMO
The syntheses of securinine and (-)-allonorsecurinine have been achieved starting from easily available alpha-amino acid derivatives and using as key steps a RCM and a Heck reaction for the formation of rings D and C, respectively. [reaction: see text]
MATERIAIS