- Design and synthesis of triglyceride analogue biotinylated suicide inhibitors for directed molecular evolution of lipolytic enzymes.
Design and synthesis of triglyceride analogue biotinylated suicide inhibitors for directed molecular evolution of lipolytic enzymes.
Bioorganic & medicinal chemistry letters (2000-09-15)
H J Deussen, S Danielsen, J Breinholt, T V Borchert
PMID10987442
RESUMO
The design, synthesis, and inhibition properties of two new triglyceride analogue biotinylated suicide inhibitors (2) and (3) for directed molecular evolution of lipolytic enzymes by phage-display is described.
MATERIAIS