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Merck
  • CuCl/CCl(4)-promoted convenient synthesis of sulfonyl amidines from tertiary amines and sulfonyl azides.

CuCl/CCl(4)-promoted convenient synthesis of sulfonyl amidines from tertiary amines and sulfonyl azides.

Organic letters (2010-02-04)
Xiaoliang Xu, Zhichuang Ge, Dongping Cheng, Lei Ma, Chunshan Lu, Qunfeng Zhang, Nan Yao, Xiaonian Li
RESUMO

Promoted by CuCl/CCl(4), a variety of sulfonyl azides and tertiary amines were successfully coupled to give sulfonyl amidine derivatives in good to excellent yields. A possible mechanism for this reaction is discussed.

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