1711268

Venlafaxine hydrochloride

United States Pharmacopeia (USP) Reference Standard

• Sinônimo(s): (+/-)-1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride, Effexor
• Fórmula empírica (Notação de Hill): C₁₇H₂₇NO₂ · HCl
• Número CAS: 99300-78-4
• Peso molecular: 313.86
• Número MDL: MFCD03658865
• Código UNSPSC: 41116107
• ID de substância PubChem: 329751491
• NACRES: NA.24

Propriedades

• grau: pharmaceutical primary standard
• família API: venlafaxine
• fabricante/nome comercial: USP
• aplicação(ões): pharmaceutical (small molecule)
• formato: neat
• cadeia de caracteres SMILES: Cl[H].COc1ccc(cc1)C(CN(C)C)C2(O)CCCCC2
• InChI: 1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H
• chave InChI: QYRYFNHXARDNFZ-UHFFFAOYSA-N
• Informações sobre genes: human ... SLC6A2(6530) , SLC6A4(6532)

Descrição

Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Venlafaxine hydrochloride USP reference standard intended for use in specified quality tests and assays.

Also used to prepare standard, system suitability, and standard stock solution for assay, impurity analysis, and performance test according to the given below monographs of United States Pharmacopeia (USP):

• Venlafaxine Hydrochloride
• Venlafaxine Tablets
• Venlafaxine Hydrochloride Extended-Release Capsules
• Desvenlafaxine

Ações bioquímicas/fisiológicas

Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity.

Nota de análise

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS09
• Frases de perigo: H411
• Declarações de precaução: P273 - P391 - P501
• Classificações de perigo: Aquatic Chronic 2
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable