PHL80556

Withanolide A

phyproof^® Reference Substance

• Sinônimo(s): (5α,6α,7α,22R)-6,7-Epoxy-5,20,22-trihydroxy-1-oxo-ergosta-2,24-dien-26-oic acid δ-lactone, Withaniol
• Fórmula empírica (Notação de Hill): C₂₈H₃₈O₆
• Número CAS: 32911-62-9
• Peso molecular: 470.60
• Número MDL: MFCD07779143
• Código UNSPSC: 41116107
• NACRES: NA.24

Propriedades

• grau: primary reference standard
• linha de produto: phyproof^® Reference Substance
• Ensaio: ≥90.0% (HPLC)
• fabricante/nome comercial: PhytoLab
• aplicação(ões): food and beverages
• formato: neat
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CC1=C(C)C(=O)O[C@H](C1)[C@](C)(O)[C@H]2CC[C@H]3[C@H]4[C@H](CC[C@]23C)[C@@]5(C)C(=O)C=CC[C@]5(O)[C@H]6O[C@@H]46
• InChI: 1S/C28H38O6/c1-14-13-20(33-24(30)15(14)2)27(5,31)18-9-8-16-21-17(10-12-25(16,18)3)26(4)19(29)7-6-11-28(26,32)23-22(21)34-23/h6-7,16-18,20-23,31-32H,8-13H2,1-5H3/t16-,17-,18-,20+,21-,22-,23-,25-,26-,27+,28-/m0/s1
• chave InChI: DXWHOKCXBGLTMQ-SFQAJKIESA-N

Descrição

Descrição geral

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Ações bioquímicas/fisiológicas

C₂₈-steroidal lactone that can induce nerve development and improve nervous system function. Potential therapeutic for neurologic disorders like Alzheimer′s and Parkinson′s disease. In primary rat cortical neurons, withanolide A significantly up-regulated IDE levels, a prominent enzyme involved in degrading amyloid β protein, which may help to clear excess amyloid β protein from an Alzheimer′s-inflicted brain.

Outras notas

This compound is commonly found in plants of the genus: lycium withania

Informações legais

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable