Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos

W2895

Sigma-Aldrich

WE-14 trifluoroacetate salt

≥98% (HPLC)

Sinônimo(s):

Chromogranin A fragment 324-337 trifluoroacetate salt, H-Trp-Ser-Lys-Met-Asp-Gln-Leu-Ala-Lys-Glu-Leu-Thr-Ala-Glu-OH trifluoroacetate salt, Human CgA 324-337 trifluoroacetate salt, Peptide WE-14 trifluoroacetate salt, WSRMDQLAKELTAE trifluoroacetate salt

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Fórmula empírica (Notação de Hill):
C72H116N18O24S · xC2HF3O2
Número CAS:
115136-18-0
Peso molecular:
1649.86 (free base basis)
Número MDL:
MFCD19686975
Código UNSPSC:
12352202
ID de substância PubChem:
329830540

Ensaio

≥98% (HPLC)

forma

powder

cor

white to tan

solubilidade

H2O: >2 mg/mL

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

OC(=O)C(F)(F)F.CSCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI

1S/C72H116N18O24S.C2HF3O2/c1-35(2)29-50(67(108)78-37(5)59(100)80-44(17-11-13-26-73)62(103)82-47(20-23-55(94)95)65(106)87-51(30-36(3)4)69(110)90-58(39(7)92)71(112)79-38(6)60(101)85-49(72(113)114)21-24-56(96)97)86-64(105)46(19-22-54(76)93)83-68(109)52(32-57(98)99)88-66(107)48(25-28-115-8)84-63(104)45(18-12-14-27-74)81-70(111)53(34-91)89-61(102)42(75)31-40-33-77-43-16-10-9-15-41(40)43;3-2(4,5)1(6)7/h9-10,15-16,33,35-39,42,44-53,58,77,91-92H,11-14,17-32,34,73-75H2,1-8H3,(H2,76,93)(H,78,108)(H,79,112)(H,80,100)(H,81,111)(H,82,103)(H,83,109)(H,84,104)(H,85,101)(H,86,105)(H,87,106)(H,88,107)(H,89,102)(H,90,110)(H,94,95)(H,96,97)(H,98,99)(H,113,114);(H,6,7)/t37-,38-,39+,42-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,58-;/m0./s1

chave InChI

FZKRZHJMJIARGO-YVXXVKOOSA-N

Ações bioquímicas/fisiológicas

WE-14 peptide is a highly conserved neuropeptide derived from Chromogranin A (Parathyroid Secretory Protein 1). It has been detected in vertebrate and invertebrate neurons and in vertebrate endocrine tissues, most notably in the adrenal, pituitary, and parathyroid glands, and has also been found in human and bovine gastro-entero-pancreatic tissues.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

S C Barkatullah et al.
Histochemistry and cell biology, 116(3), 255-262 (2001-10-31)
Immunohistochemical investigation of the post-translational processing of chromogranin A (CgA) to generate WE-14 in the sympathoadrenal cell lineage of the developing porcine fetus (F) detected intense CgA and weak WE-14 immunoreactivity in migrating neuroblast cells of the diffuse sympathetic ganglia
Chromogranin A and its derived peptides in the rat and porcine gastro-entero-pancreatic system. Expression, localization, and characterization.
W J Curry et al.
Advances in experimental medicine and biology, 482, 205-213 (2001-02-24)
Colocalization of WE-14 immunostaining with the classical islet hormones in the porcine pancreas.
W J Curry et al.
Advances in experimental medicine and biology, 426, 139-144 (1997-01-01)
W J Curry et al.
Regulatory peptides, 113(1-3), 41-47 (2003-04-11)
WE-14 is derived from the cell-specific posttranslational processing of chromogranin A (CgA) in subpopulations of neuroendocrine cells and neurons. Region- and site-specific chromogranin A, pancreastatin and WE-14 antisera were employed to study the generation of WE-14 in porcine ocular tissues.
P Norlén et al.
Regulatory peptides, 70(2-3), 121-133 (1997-06-18)
The ECL cells constitute the predominant endocrine cell population in the mucosa of the acid-secreting part of the stomach (fundus). They are rich in chromogranin A (CGA), histamine and histidine decarboxylase (HDC). They secrete CGA-derived peptides and histamine in response
Exibir todos os documentos relacionados

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica