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Sigma-Aldrich

(S)-(+)-Mephenytoin

≥98% (HPLC), solid, CYP2B6 & CYP2C19 substrate

Sinônimo(s):

(S)-(+)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione, (S)-(+)-5-Ethyl-3-methyl-5-phenylhydantoin

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About This Item

Fórmula empírica (Notação de Hill):
C12H14N2O2
Número CAS:
70989-04-7
Peso molecular:
218.25
Número MDL:
MFCD00270025
Código UNSPSC:
12161501
ID de substância PubChem:
24724646
NACRES:
NA.77

product name

(S)-(+)-Mephenytoin, solid, ≥98% (HPLC)

Ensaio

≥98% (HPLC)

forma

solid

cor

off-white

pf

135-138 °C

solubilidade

DMSO: soluble

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

CC[C@]1(NC(=O)N(C)C1=O)c2ccccc2

InChI

1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m0/s1

chave InChI

GMHKMTDVRCWUDX-LBPRGKRZSA-N

Aplicação

S-Mephenytoin has been used as a CYP2C19 substrate for the analysis of cytochrome P450 metabolism. S-Mephenytoin has also been used as probe substrates for LC/MS-based analysis of relative activity factor (RAF).

Ações bioquímicas/fisiológicas

CYP2B6 & CYP2C19 substrate. Methenytoin isomer. Anticonvulsant; antiepileptic.

Características e benefícios

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Nota de preparo

(S)-(+)-Mephenytoin is soluble in DMSO.

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H302,H315,H319,H335

Classificações de perigo

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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