Selecione um tamanho
500 μG
R$ 2.443,00
1 MG
R$ 4.654,00
Selecione um tamanho
Alterar visualização
500 μG
R$ 2.443,00
1 MG
R$ 4.654,00
About This Item
Código UNSPSC:
12352200
NACRES:
NA.32
Produtos recomendados
![[Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone trifluoroacetate salt ≥95% (HPLC)](/deepweb/assets/sigmaaldrich/product/structures/276/187/9733edf4-6412-4f2b-8cc6-c3f9f3425d4d/640/9733edf4-6412-4f2b-8cc6-c3f9f3425d4d.png)
Formulário
lyophilized powder
Nível de qualidade
cor
white
solubilidade
deionized water: soluble
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
Amino Acid Sequence
H-THR-LEU-GLN-PRO-PRO-SER-ALA-LEU-ARG-ARG-ARG-HIS-TYR-HIS-HIS-ALA-LEU-PRO-PRO-SER-ARG-OH
Descrição geral
TLQP-21 peptide is a derivative of VGF and is expressed at higher levels in the brain.[1]
Ações bioquímicas/fisiológicas
TLQP-21 peptide is involved in the central and peripheral nervous system activities such as regulating reproductive and circadian behaviors, feeding, and body weight. It is also involved in regulating neuropathic pain and peripheral adiposity.[1] TLQP-21 plays a role in stimulating the secretion of insulin and prevents apoptosis of pancreatic cells.[2] It also activates the complement C3a receptor-1 (C3aR1) in the brain.[1]
forma física
Lyophilized from 0.1% aqueous TFA
Outras notas
Lyophilized from 0.1% TFA in H2O
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Escolha uma das versões mais recentes:
Certificados de análise (COA)
Lot/Batch Number
Não está vendo a versão correta?
Se precisar de uma versão específica, você pode procurar um certificado específico pelo número do lote ou da remessa.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Wei Zhang et al.
PloS one, 8(11), e79760-e79760 (2013-11-28)
Hyperglycemia causes oxidative stress that could damage vascular endothelial cells, leading to cardiovascular complications. The Vgf gene was identified as a nerve growth factor-responsive gene, and its protein product, VGF, is characterized by the presence of partially cleaved products. One
Farida El Gaamouch et al.
Molecular neurodegeneration, 15(1), 4-4 (2020-01-12)
Multiomic studies by several groups in the NIH Accelerating Medicines Partnership for Alzheimer's Disease (AMP-AD) identified VGF as a major driver of Alzheimer's disease (AD), also finding that reduced VGF levels correlate with mean amyloid plaque density, Clinical Dementia Rating
C Severini et al.
British journal of pharmacology, 157(6), 984-993 (2009-05-27)
Vgf gene expression has been detected in various endocrine and neuronal cells in the gastrointestinal tract. In this study we investigated the pharmacological activity of different VGF-derived peptides. Among these, TLQP-21, corresponding to the 556-576 fragment of the protein was
A Bartolomucci et al.
Proceedings of the National Academy of Sciences of the United States of America, 103(39), 14584-14589 (2006-09-20)
The vgf gene has been identified as an energy homeostasis regulator. Vgf encodes a 617-aa precursor protein that is processed to yield an incompletely characterized panel of neuropeptides. Until now, it was an unproved assumption that VGF-derived peptides could regulate
Huan Liu et al.
Autophagy, 16(12), 2140-2155 (2020-01-22)
Mesenchymal stem cell (MSC) transplantation has been widely applied as a potential therapeutic for multiple diseases. However, the underlying therapeutic mechanisms are not fully understood, especially the paradox between the low survival rate of transplanted cells and the beneficial therapeutic
Active Filters
Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.
Entre em contato com a assistência técnica
