SRP6278

TDRD12-BD2 (908-999) his tag human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Sinônimo(s): ECAT8
• Código UNSPSC: 12352200
• NACRES: NA.32

Propriedades

• fonte biológica: human
• recombinante: expressed in E. coli
• Ensaio: ≥98% (SDS-PAGE)
• Formulário: liquid
• peso molecular: 13 kDa
• embalagem: pkg of 1 mg; pkg of 100 μg; pkg of 20 μg
• concentração: 2 mg/mL
• nº de adesão UniProt: Q587J7
• Condições de expedição: dry ice
• temperatura de armazenamento: −70°C
• Informações sobre genes: human ... TDRD12(91646)

Descrição

Descrição geral

Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor domains occur either alone, in tandem, or with other domains and are found in many proteins that are involved in RNA metabolism, germ cell development, transposon silencing, DNA damage response, histone modification, and chromatin remodeling. The tudor domains recognize symmetric methylated arginine or methylated lysine residues. Tudor domain proteins act as an oncogene and play a very important role in HCC and colon cancer. TDRD is also involved in RISC complex and interacts with AEG-1 oncogene. The tudor domain can bind to methylated arginine protein and promote tumor angiogenesis in human hepatocellular carcinoma, etc. The recombinant protein includes TDRD12 (domain 908-999aa) with N-terminal His-tag.

forma física

rh-TDRD12-BD2 is supplied as a solution in PBS Buffer containing 10% glycerol.

Informações de segurança

• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable