MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. MIP-1γ signals through the CCR1 receptor. MIP-1γ chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1g contains six cysteines including the four highly conserved cysteine residues present in CC chemokines. Recombinant murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.
Ações bioquímicas/fisiológicas
MIP-1g is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog. Recombinant murine MIP-1g is an 11.6 kDa protein containing 101 amino acid residues.
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
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