SML1238

Ertapenem sodium

≥90% (HPLC), powder, carbopenem antibiotic

• Sinônimo(s): (4R,5S,6S)-3-[(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid sodium, ZD-443 sodium
• Fórmula empírica (Notação de Hill): C₂₂H₂₄N₃O₇S · Na
• Número CAS: 153773-82-1
• Peso molecular: 497.50
• Código UNSPSC: 51111800
• NACRES: NA.77

Propriedades

• product name: Ertapenem sodium, ≥90% (HPLC)
• Nível de qualidade: 100
• Ensaio: ≥90% (HPLC)
• forma: powder
• condição de armazenamento: desiccated; protect from light
• cor: white to beige
• solubilidade: H₂O: 20 mg/mL, clear
• Condições de expedição: wet ice
• temperatura de armazenamento: −70°C
• InChI: 1S/C22H25N3O7S.Na/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30;/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32);/q;+1/p-1/t9-,10-,13+,14+,15-,16-;/m1./s1
• chave InChI: ZXNAQFZBWUNWJM-HRXMHBOMSA-M

Descrição

Aplicação

Ertapenem sodium has been used as a carbapenem in the NitroSpeed-Carba NP test in minimum inhibitory concentration (MIC) testing for differentiation of carbapenemases in Enterobacterales and Pseudomonas aeruginosa. It has also been used as an antibiotic to study its effects on the survival of septic mice.

Ações bioquímicas/fisiológicas

Ertapenem is a broad spectrum carbopenem antibiotic. Ertapenem is active against both gram-positive and gram-negative bacteria. Ertapenem shows an extended duration of action in vivo due to its reversible binding to serum protein.

Ertapenem sodium exhibits its activity against several aerobic and anaerobic microorganisms and is more resistant to β-lactamase enzymes. It has been studied in the treatment of several infectious diseases.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable