SML1042

Eptifibatide acetate

≥98% (HPLC)

• Sinônimo(s): Cyclo(S,S)-Mpr(Har)GDWPC-NH2 acetate, N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide cyclic (16)-disulfide acetate
• Fórmula empírica (Notação de Hill): C₃₅H₄₉N₁₁O₉S₂ · xC₂H₄O₂
• Número CAS: 881997-86-0
• Peso molecular: 831.96 (free base basis)
• Código UNSPSC: 51111800
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• Formulário: powder
• condição de armazenamento: desiccated
• cor: white to beige
• solubilidade: H₂O: 2 mg/mL, clear (warmed)
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C

Descrição

Descrição geral

Eptifibatide acetate is a cyclic heptapeptide.[1] It is the member of the class arginin-glycin-aspartat-mimetics.[2] Eptifibatide has a short half-life.[3] The drug decreases the risk of myocardial infarction (MI).[4] Eptifibatide acetate might be associated with thrombocytopenia.[2]

Ações bioquímicas/fisiológicas

Eptifibatide is a specific inhibitor of fibrinogen binding to the platelet membrane integrin glycoprotein GPIIb/IIIa receptor, preventing platelet aggregation. Eptifibatide binds reversibly and competitively.

Eptifibatide is a specific inhibitor of fibrinogen binding to the platelet membrane integrin glycoprotein GPIIb/IIIa receptor.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable