SML0983

5F-203

≥98% (HPLC)

• Sinônimo(s): 4-(5-Fluoro-2-benzothiazolyl)-2-methyl-benzenamine, 5F203, NSC-703786
• Fórmula empírica (Notação de Hill): C₁₄H₁₁FN₂S
• Número CAS: 260443-89-8
• Peso molecular: 258.31
• Código UNSPSC: 12352200
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• Formulário: powder
• cor: white to beige
• solubilidade: DMSO: 20 mg/mL, clear
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: Fc1cc2nc([s]c2cc1)c3cc(c(cc3)N)C
• InChI: 1S/C14H11FN2S/c1-8-6-9(2-4-11(8)16)14-17-12-7-10(15)3-5-13(12)18-14/h2-7H,16H2,1H3
• chave InChI: IFWLHIIUGSEKKE-UHFFFAOYSA-N

Descrição

Ações bioquímicas/fisiológicas

5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death.

5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death. 5F-203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. Treatment of cells with 5F-203 also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK.

Características e benefícios

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Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H302
• Declarações de precaução: P264 - P270 - P301 + P312 - P501
• Classificações de perigo: Acute Tox. 4 Oral
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable