SML0500

GSK334429 hydrochloride

≥98% (HPLC)

• Sinônimo(s): 1-(1-Methylethyl)-4-((1-(6-(trifluoromethyl)-3-pyridinyl)-4-piperidinyl)carbonyl)hexahydro-1H-1,4-diazepine hydrochloride
• Fórmula empírica (Notação de Hill): C₂₀H₂₉F₃N₄O · xHCl
• Número CAS: 799558-94-4
• Peso molecular: 398.47 (free base basis)
• Número MDL: MFCD22666404
• Código UNSPSC: 12352200
• ID de substância PubChem: 329825449
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• Formulário: powder
• condição de armazenamento: desiccated
• cor: white to beige
• solubilidade: H₂O: 5 mg/mL (clear solution)
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: Cl.CC(C)N1CCCN(CC1)C(=O)C2CCN(CC2)c3ccc(nc3)C(F)(F)F
• InChI: 1S/C20H29F3N4O.ClH/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23;/h4-5,14-16H,3,6-13H2,1-2H3;1H
• chave InChI: RCZVWLOXPFGZDD-UHFFFAOYSA-N

Descrição

Ações bioquímicas/fisiológicas

GSK334429 is a selective histamine H3 receptor antagonist.

GSK334429 is a selective histamine H3 receptor antagonist. H3 antagonists increase the release of brain histamine, ACh, NE and DA neurotransmitters that modulate cognitive processes. Studies look at their analgesic efffects including efficacy for neuropathic pain.

Características e benefícios

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Outras notas

Store desiccated; dry room.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable