SMB01019

Amorfrutin A

≥90% (LC/MS-ELSD)

• Sinônimo(s): 2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)-6-(2-phenylethyl)benzoic acid, 3-hydroxy-4-isopentenyl-5-methoxybibenzyl-2-carboxylic acid
• Fórmula empírica (Notação de Hill): C₂₁H₂₄O₄
• Número CAS: 80489-90-3
• Peso molecular: 340.41
• Número MDL: MFCD23703108
• Código UNSPSC: 12352205
• NACRES: NA.25

Propriedades

• fonte biológica: plant
• Ensaio: ≥90% (LC/MS-ELSD)
• forma: solid
• peso molecular: 340.41
• solubilidade: water: slightly soluble
• aplicação(ões): metabolomics; vitamins, nutraceuticals, and natural products
• temperatura de armazenamento: −20°C
• InChI: 1S/C21H24O4/c1-14(2)9-12-17-18(25-3)13-16(19(20(17)22)21(23)24)11-10-15-7-5-4-6-8-15/h4-9,13,22H,10-12H2,1-3H3,(H,23,24)
• chave InChI: CTNFTPUIYFUXBE-UHFFFAOYSA-N

Descrição

Descrição geral

Amorfrutin A is a stilbenoid compound commonly present in plants like Glycyrrhiza foetida, Glycyrrhiza acanthocarpa, Cajanus cajan, and Amorpha fruticosa. Current research indicates that this naturally occurring metabolite possesses diverse biological activities, including anti-inflammatory, anticancer, antidiabetic, and antimicrobial properties.

Aplicação

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Ações bioquímicas/fisiológicas

According to the existing research, Amorfrutin-A demonstrated its ability to inhibit NF-κB activity, a pivotal regulator of genes governing a wide range of cellular functions, such as immune responses, apoptosis, tumor growth, and tissue development. Furthermore, it exhibits anti-inflammatory properties in colon cells by interacting with the nuclear receptor PPARγ, resulting in the reduced expression and secretion of inflammatory mediators. This suggests its potential for treating conditions like inflammatory bowel diseases. Additionally, it also exhibited antidiabetic activity through binding to and activating the nuclear receptor PPARγ.

Características e benefícios

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Outras notas

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Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable