SMB00806

7-Ketodeoxycholic acid

≥95% (HPLC)

• Sinônimo(s): 3α,12α-Dihydroxy-7-oxo-5β-cholanoic acid, 7-Oxo-3α,12α-dihydroxy-5β-cholanoic acid
• Fórmula empírica (Notação de Hill): C₂₄H₃₈O₅
• Número CAS: 911-40-0
• Peso molecular: 406.56
• Código UNSPSC: 41141802
• NACRES: NA.28

Propriedades

• Ensaio: ≥95% (HPLC)
• Formulário: powder
• embalagem: pkg of 1 g; pkg of 50 mg
• cor: off-white to beige
• pf: 193—198 °C
• grupo funcional: carboxylic acid; ketone
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O[C@@H]1[C@]2([C@H]([C@H]3[C@@H]([C@@]4([C@@H](C[C@@H](CC4)O)CC3=O)C)C1)CC[C@@H]2[C@@H](CCC(=O)O)C)C
• InChI: 1S/C24H38O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-18,20,22,25,27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,20+,22+,23+,24-/m1/s1
• chave InChI: RHCPKKNRWFXMAT-RRWYKFPJSA-N

Descrição

Descrição geral

7-Ketodeoxycholic acid, categorized as a oxo-5beta-cholanic acid, is a bile acid derivative and a metabolite resulting from the degradation of the primary bile acid, cholic acid, by intestinal bacteria. Bile acids, natural steroid amphipathic compounds formed through cholesterol oxidation in the liver, play a crucial role in regulating lipid metabolism. They facilitate the digestion, absorption, and transport of lipids, lipid-soluble vitamins, and related molecules in the gastrointestinal tract. These bile acids also impact various aspects of cholesterol, glucose, and energy balance. However, in specific liver conditions such as intrahepatic cholestasis characterized by reduced bile flow, the accumulation of bile acids at elevated concentrations can lead to severe toxic effects. This makes 7-Ketodeoxycholic acid a compound of interest for biochemical and metabolomics research.

Aplicação

7-Ketodeoxycholic acid finds application in metabolomics, biochemical and microbiome research.

Características e benefícios

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

Outras notas

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Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable