This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Imunogênio
A phospho specific peptide corresponding to residues surrounding Y419 of human Phospho-Src-Y419
forma física
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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