SAB5701800

Anti-Phospho-CDK9-T186 antibody produced in rabbit

• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: liquid
• reatividade de espécies: human, mouse, rat
• concentração: 1.64 mg/mL
• técnica(s): western blot: 1:500-1:2000
• nº de adesão UniProt: P50750
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pThr186)
• Informações sobre genes: human ... CDK9(1025)

Descrição

Descrição geral

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Imunogênio

A synthetic phosphorylated peptide around T186 of human CDK9 (NP_001252.1).

forma física

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Informações de segurança

• Código de classe de armazenamento: 12 - Non Combustible Liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable