Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008]
Imunogênio
A synthesized peptide derived from human Heme Oxygenase 1 (HO-1/HMOX1) (HO-1/HMOX1)
forma física
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
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